Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23934092 | 0.93 | CHRM2 (0.58) | CHRM2LMNAPIK3CDTDP1 | |
| SCHEMBL12589253 | 0.91 | CHRM2 (0.54) | CHRM2PIK3CDTDP1CYP2C9CYP2C19 | |
| SCHEMBL20755899 | 0.91 | CHRM2 (0.48) | CHRM2LMNAPIK3CDCYP2C9CYP2C19 | |
| SCHEMBL4122365 | 0.87 | LMNA (0.43) | CHRM2LMNAPIK3CD | |
| SCHEMBL29580455 | 0.85 | LMNA (0.41) | CHRM2LMNAPIK3CD | |
| SCHEMBL29580790 | 0.85 | LMNA (0.41) | CHRM2LMNAPIK3CD | |
| SCHEMBL20755531 | 0.83 | CHRM2 (0.39) | CHRM2LMNAPIK3CD | |
| SCHEMBL10704491 | 0.83 | CHRM2 (0.50) | CHRM2PIK3CDTDP1CYP2C9CYP2C19 | |
| SCHEMBL12039802 | 0.82 | LMNA (0.39) | CHRM2LMNAPIK3CD | |
| SCHEMBL8405817 | 0.82 | CHRM2 (0.48) | CHRM2LMNAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293706-A1 | Multicomponent Delivery Systems for Polyanionic Cargo Compound Delivery | MEDICI THERAPEUTICS, INC. | 2023-09-21 | — | — | US | disclosed |
| US-20230041050-A1 | LOW VOLATILE POLYAMINE SALTS OF ANIONIC PESTICIDES | BASF CORPORATION | 2023-02-09 | — | — | US | disclosed |
| US-20210322575-A1 | LIPID NANOPARTICLE FORMULATIONS COMPRISING LIPIDATED CATIONIC PEPTIDE COMPOUNDS FOR NUCLEIC ACID DELIVERY | NUTCRACKER THERAPEUTICS, INC. (US) | 2021-10-21 | — | — | US | disclosed |
| US-11041069-B2 | Gene delivery carrier | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-22 | — | — | US | disclosed |
| US-20190194444-A1 | GENE DELIVERY CARRIER | POLITECNICO DI MILANO (IT) | 2019-06-27 | — | — | US | disclosed |
| US-8562966-B2 | End-modified poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-10-22 | — | — | US | disclosed |
| US-20120149630-A1 | END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-06-14 | — | — | US | disclosed |
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194444-A1 | GENE DELIVERY CARRIER | PAICS, PBDC1, BCAT1 | CHRM2 4884/4885LMNA 330/4885PIK3CD 941/4885 |
| US-20120149630-A1 | END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF | PARN, PARG, POLL | CHRM2 4646/4885LMNA 566/4885PIK3CD 1243/4885 |
| US-20230293706-A1 | Multicomponent Delivery Systems for Polyanionic Cargo Compound Delivery | MTREX, EXOSC5, KPNA6 | CHRM2 4843/4885LMNA 474/4885PIK3CD 1443/4885 |
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | PARN, PARG, POLL | CHRM2 4646/4885LMNA 566/4885PIK3CD 1243/4885 |
| US-20210322575-A1 | LIPID NANOPARTICLE FORMULATIONS COMPRISING LIPIDATED CATIONIC PEPTIDE COMPOUNDS FOR NUCLEIC ACID DELIVERY | PHOSPHO1, PLIN3, CETP | CHRM2 4879/4885LMNA 213/4885PIK3CD 772/4885 |
| US-11041069-B2 | Gene delivery carrier | PAICS, PBDC1, BCAT1 | CHRM2 4884/4885LMNA 330/4885PIK3CD 941/4885 |
| US-20230041050-A1 | LOW VOLATILE POLYAMINE SALTS OF ANIONIC PESTICIDES | SRM, SMS, SMOX | CHRM2 331/4885LMNA 2821/4885PIK3CD 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.