Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419080 | 0.86 | SIGMAR1 (0.56) | SIGMAR1CYP19A1CHRNB2CHRNA4HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28923744 | 0.84 | — | — | |
| SCHEMBL9948343 | 0.83 | SIGMAR1 (0.42) | SIGMAR1CHRNB2CHRNA4TDP1MEN1 | |
| SCHEMBL27027263 | 0.78 | CYP19A1 (0.41) | SIGMAR1CYP19A1CHRNB2CHRNA4ALOX15 | |
| SCHEMBL27027262 | 0.78 | CYP19A1 (0.41) | SIGMAR1CYP19A1CHRNB2CHRNA4ALOX15 | |
| SCHEMBL30322863 | 0.74 | MAOA (0.47) | SIGMAR1CYP19A1HSD17B10CYP11B2CYP11B1 | |
| SCHEMBL2239784 | 0.74 | MAOA (0.47) | SIGMAR1CYP19A1HSD17B10CYP11B2CYP11B1 | |
| SCHEMBL3075871 | 0.74 | MAOA (0.47) | SIGMAR1CYP19A1HSD17B10CYP11B2CYP11B1 | |
| SCHEMBL30322772 | 0.74 | MAOA (0.47) | SIGMAR1CYP19A1HSD17B10CYP11B2CYP11B1 | |
| SCHEMBL22270054 | 0.74 | FNTA (0.38) | SIGMAR1CYP19A1CHRNB2CHRNA4CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334384-B2 | Process for preparing tetrahydrotetraazapentacenes and derivatives | XEROX CORPORATION (US) | 2012-12-18 | — | — | US | disclosed |
| US-8283659-B2 | Tetrahydrotetraazapentacenes in thin-film transistors | XEROX CORPORATION (US) | 2012-10-09 | — | — | US | disclosed |
| US-20120161108-A1 | TETRAHYDROTETRAAZAPENTACENES IN THIN-FILM TRANSISTORS | XEROX CORPORATION (US) | 2012-06-28 | — | — | US | disclosed |
| US-20120165529-A1 | PROCESS FOR PREPARING TETRAHYDROTETRAAZAPENTACENES AND DERIVATIVES | XEROX CORPORATION (US) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120161108-A1 | TETRAHYDROTETRAAZAPENTACENES IN THIN-FILM TRANSISTORS | CYP4Z1, TCF4, TERT | SIGMAR1 2955/4885CYP19A1 299/4885CHRNB2 1461/4885 |
| US-20120165529-A1 | PROCESS FOR PREPARING TETRAHYDROTETRAAZAPENTACENES AND DERIVATIVES | DHPS, TBXA2R, DHRS9 | SIGMAR1 2317/4885CYP19A1 113/4885CHRNB2 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.