Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | CENPE | Q02224 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574241 | 0.92 | MLYCD (0.35) | MLYCDCENPEGAAHTTGFER | |
| SCHEMBL9957726 | 0.86 | MLYCD (0.34) | MLYCDCENPEGAAHTTGFER | |
| SCHEMBL9958598 | 0.82 | CYP2C19 (0.36) | CENPEGAAHTTGFEROPRM1 | |
| SCHEMBL3574242 | 0.79 | CYP2C19 (0.37) | CENPEGAAHTTGFEROPRM1 | |
| SCHEMBL3584062 | 0.76 | GBA1 (0.34) | MLYCDCENPEGBA1OPRM1OPRD1 | |
| SCHEMBL3574238 | 0.75 | MLYCD (0.35) | MLYCDCENPEOPRM1OPRD1CYP2C19 | |
| SCHEMBL3580029 | 0.74 | MLYCD (0.34) | MLYCDCENPEOPRM1OPRD1CYP2C19 | |
| SCHEMBL3579944 | 0.71 | MCHR1 (0.39) | MLYCDOPRM1OPRD1 | |
| SCHEMBL9957640 | 0.70 | C5AR1 (0.37) | MLYCDHTTCYP2C19MCL1 | |
| SCHEMBL1397658 | 0.69 | TRPM8 (0.37) | CETPMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |