SCHEMBL998345

SCHEMBL998345

[O]c1ccc(-c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
TAAR1 Q96RJ0 2/20 0.50
MAPK1 P28482 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
MAPT P10636 2/20 0.46
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LMNA P02545 2/20 0.44
HTT P42858 2/20 0.44
ABCC4 O15439 1/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57499 1.00 ALDH1A1 (0.60) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
SCHEMBL11899848 0.90 ALDH1A1 (0.44) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
SCHEMBL9936836 0.89 KMO (0.52) ALDH1A1TAAR1CYP3A4CA2MAPT
SCHEMBL14677847 0.86 ALDH1A1 (0.38) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
SCHEMBL18674172 0.82 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
Tannin Pyrogallol SCHEMBL21448 0.82 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
SCHEMBL1991754 0.82 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
Tannin Pyrogallol SCHEMBL11689471 0.82 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
SCHEMBL827097 0.82 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
SCHEMBL2637802 0.82 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105431408-B Compound, material for organic electroluminescent element, and electronic device 出光兴产株式会社 2022-04-15 CN disclosed
EP-3312159-B1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO (JP) 2022-01-26 EP disclosed
EP-3127894-B1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO (JP) 2021-04-28 EP disclosed
US-10944057-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2021-03-09 US disclosed
CN-105531278-B Compound, material for organic electroluminescent element, and electronic device 出光兴产株式会社 2021-01-26 CN disclosed
CN-105658620-B Compound, material for organic electroluminescent element, and electronic device 出光兴产株式会社 2020-12-29 CN disclosed
US-10854822-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2020-12-01 US disclosed
US-10790449-B2 Compound, material for organic electroluminescence element, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2020-09-29 US disclosed
US-10756275-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2020-08-25 US disclosed
US-10629821-B2 Compound, material for organic electroluminescent elements using same, and organic electroluminescent element and electronic device each using same IDEMITSU KOSAN CO., LTD. (JP) 2020-04-21 US disclosed
EP-2293650-A1 Dipyrrolo[a,h]pyrenes for organic light-emitting devices Samsung Mobile Display Co., Ltd. (KR) 2011-03-09 EP disclosed
EP-2292602-A1 Phenaleno[1,9-fg]indole based organic light-emitting devices Samsung Mobile Display Co., Ltd. (KR) 2011-03-09 EP disclosed
US-20110049488-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-03-03 US disclosed
US-20110049484-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-03-03 US disclosed
US-20110049494-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-03-03 US disclosed
US-20110049490-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-03-03 US disclosed
US-20110017983-A1 POLYMER AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME IDEMITSU KOSAN CO., LTD. 2011-01-27 US disclosed
US-20100219400-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-09-02 US disclosed
EP-2085382-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-08-05 EP disclosed
US-20080124572-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10944057-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic equipment OR10J3, KCNA5, KCNK10 ALDH1A1 835/4885TAAR1 1157/4885MAPK1 2016/4885
US-10790449-B2 Compound, material for organic electroluminescence element, organic electroluminescence element, and electronic device RPL19, LEF1, RPL39 ALDH1A1 969/4885TAAR1 1082/4885MAPK1 2112/4885
US-20110049494-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME INMT, TYR, HTT ALDH1A1 1062/4885TAAR1 256/4885MAPK1 3616/4885
US-10854822-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device ESR1, L1CAM, ELAVL1 ALDH1A1 959/4885TAAR1 768/4885MAPK1 1101/4885
US-10756275-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic equipment CHRM1, L1CAM, ESR1 ALDH1A1 160/4885TAAR1 939/4885MAPK1 1408/4885
US-20110049490-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME TRPC1, TRPC4, LAGE3 ALDH1A1 470/4885TAAR1 1955/4885MAPK1 2072/4885
US-20110049484-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME INMT, TYR, HTT ALDH1A1 1062/4885TAAR1 256/4885MAPK1 3616/4885
US-10629821-B2 Compound, material for organic electroluminescent elements using same, and organic electroluminescent element and electronic device each using same OR10J3, LEF1, PIEZO1 ALDH1A1 1311/4885TAAR1 2613/4885MAPK1 1684/4885
US-20110049488-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME TRPC1, TRPC4, LAGE3 ALDH1A1 470/4885TAAR1 1955/4885MAPK1 2072/4885
US-20080124572-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, DDC, AOC2 ALDH1A1 181/4885TAAR1 349/4885MAPK1 1670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.