Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849215 | 0.89 | PARP10 (0.42) | RAB9ANPC1L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL247590 | 0.86 | CES2 (0.59) | RAB9ANPC1L3MBTL1SMN1; SMN2CES2 | |
| SCHEMBL28775846 | 0.86 | CES2 (0.59) | RAB9ANPC1L3MBTL1SMN1; SMN2CES2 | |
| SCHEMBL28343283 | 0.82 | CES2 (0.54) | RAB9ANPC1L3MBTL1SMN1; SMN2CES2 | |
| SCHEMBL9994270 | 0.81 | RAB9A (0.56) | RAB9ANPC1L3MBTL1SMN1; SMN2CES2 | |
| SCHEMBL18050295 | 0.80 | CES2 (0.52) | RAB9ANPC1L3MBTL1SMN1; SMN2CES2 | |
| SCHEMBL2145960 | 0.80 | LMNA (0.53) | RAB9ANPC1TSHRALDH1A1LMNA | |
| SCHEMBL18050293 | 0.80 | CES2 (0.52) | RAB9ANPC1L3MBTL1SMN1; SMN2CES2 | |
| SCHEMBL28343284 | 0.80 | ALOX15 (0.56) | RAB9ANPC1L3MBTL1SMN1; SMN2CES2 | |
| SCHEMBL6444130 | 0.78 | ALDH1A1 (0.52) | RAB9ANPC1L3MBTL1SMN1; SMN2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825611-B | 4(1H) -quinovone derivatives and uses thereof | 刘扶东 | 2022-09-09 | — | — | CN | disclosed |
| EP-3801533-A1 | DOSING REGIMEN FOR THE TREATMENT OF PI3K RELATED DISORDERS | Incyte Corporation (US) | 2021-04-14 | — | — | EP | disclosed |
| CN-111825611-A | 4(1H) -quinovone derivatives and uses thereof | 中央研究院 | 2020-10-27 | — | — | CN | disclosed |
| US-8987504-B2 | Aminohydroxylation of alkenes | VICTORIA LINK LIMITED (NZ) | 2015-03-24 | — | — | US | disclosed |
| US-20130274479-A1 | AMINOHYDROXYLATION OF ALKENES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2013-10-17 | — | — | US | disclosed |
| WO-2011159177-A1 | IMPROVED AMINOHYDROXYLATION OF ALKENES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2011-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274479-A1 | AMINOHYDROXYLATION OF ALKENES | ALKBH3, ALKBH1, ALKBH2 | RAB9A 3665/4885NPC1 3997/4885L3MBTL1 4186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.