SCHEMBL1000178

SCHEMBL1000178

Nc1cc(N)cc(CC(=O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.48
GABRD O14764 2/20 0.48
GABRA1 P14867 2/20 0.48
GABRB1 P18505 2/20 0.48
GABRG2 P18507 2/20 0.48
GABRB3 P28472 2/20 0.48
GABRA5 P31644 2/20 0.48
GABRA3 P34903 2/20 0.48
GABRA2 P47869 2/20 0.48
GABRB2 P47870 2/20 0.48
GABRA4 P48169 2/20 0.48
GABRE P78334 2/20 0.48
GABRA6 Q16445 2/20 0.48
GABRG1 Q8N1C3 2/20 0.48
GABRG3 Q99928 2/20 0.48
GABRQ Q9UN88 2/20 0.48
AKR1B1 P15121 1/20 0.48
KDM4E B2RXH2 3/20 0.45
MAPT P10636 3/20 0.45
HPGD P15428 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5193481 0.95 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL8862011 0.87 CA2 (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17161269 0.85 GABRA1 (0.42) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL10605792 0.85 LMNA (0.42) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL583915 0.81 AKR1B1 (0.60) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL27590164 0.80 PTGS1 (0.58) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL18739941 0.80 CA2 (0.48) KDM4ELMNAPOLBCA2HTT
SCHEMBL7083788 0.79 NPC1 (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL21999361 0.78 POLB (0.38) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL1000775 0.78 GABRP (0.47) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011301-A Preparation method and application of photo-thermal dual-curing-based 3D printing polyimide slurry 南京工业大学 2026-05-12 CN claimed
CN-122011301-A Preparation method and application of photo-thermal dual-curing-based 3D printing polyimide slurry 南京工业大学 2026-05-12 CN disclosed
CN-116144176-B Polyimide composition, film, preparation method and application thereof 山东华夏神舟新材料有限公司 2023-08-15 CN disclosed
CN-116144176-A Polyimide composition, film, preparation method and application thereof 山东华夏神舟新材料有限公司 2023-05-23 CN disclosed
CN-111116912-B Polyimide resin, preparation method thereof and method for preparing polyimide film/cross-linked polyimide film by using polyimide resin 山东华夏神舟新材料有限公司 2022-12-06 CN disclosed
CN-114437522-A High-temperature-resistant PET-PI composite film and adhesive tape thereof 苏州世华新材料科技股份有限公司 2022-05-06 CN disclosed
US-20200148937-A1 INHIBITING HYDROCARBON HYDRATE AGGLOMERATION COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2020-05-14 US disclosed
CN-111116912-A Polyimide resin, preparation method thereof and method for preparing polyimide film/cross-linked polyimide film by using polyimide resin 山东华夏神舟新材料有限公司 2020-05-08 CN disclosed
US-20150062519-A1 ALIGNMENT FILM, COMPOSITION FOR FORMING ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC (JP) 2015-03-05 US disclosed
US-8906474-B2 Alignment film, composition for forming alignment film and liquid crystal display device JAPAN DISPLAY INC. (JP) 2014-12-09 US disclosed
US-20080234380-A1 Compositions and method for treatment of chronic inflammatory diseases SHAPIRO HOWARD K 2008-09-25 US disclosed
US-20080171783-A1 COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE MIGENIX INC. (CA) 2008-07-17 US disclosed
EP-1910279-A2 NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF MIGENIX INC. (CA) 2008-04-16 EP disclosed
US-20070021434-A1 NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF MIGENIX INC. (CA) 2007-01-25 US disclosed
WO-2007002639-A2 NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF MIGENIX INC. (CA) 2007-01-04 WO disclosed
US-20050153876-A1 Compositions of lipopeptide antibiotic derivatives and methods of use thereof MIGENIX INC. (CA) 2005-07-14 US disclosed
US-20050090553-A1 Compositions and method for treatment of chronic inflammatory diseases SECANT PHARMA, LLC 2005-04-28 US disclosed
EP-0759750-A4 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1998-05-27 EP disclosed
EP-0759750-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO, Howard, K. (US) 1997-03-05 EP disclosed
WO-1995031194-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1995-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021434-A1 NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF HAVCR2, ADAR, NSUN2 GABRP 4559/4885GABRD 3304/4885GABRA1 4335/4885
US-20200148937-A1 INHIBITING HYDROCARBON HYDRATE AGGLOMERATION H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, AHR, SHH GABRP 4773/4885GABRD 4546/4885GABRA1 4125/4885
US-20050090553-A1 Compositions and method for treatment of chronic inflammatory diseases PCCA, HMGB1, PTGES GABRP 1135/4885GABRD 2421/4885GABRA1 1243/4885
US-20050153876-A1 Compositions of lipopeptide antibiotic derivatives and methods of use thereof NRDC, NOD2, NGLY1 GABRP 2692/4885GABRD 2030/4885GABRA1 4039/4885
US-20080234380-A1 Compositions and method for treatment of chronic inflammatory diseases HMGB1, PCCA, QSOX1 GABRP 1001/4885GABRD 2292/4885GABRA1 1011/4885
US-20080171783-A1 COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE POLQ, POLI, POLH GABRP 3374/4885GABRD 3877/4885GABRA1 4498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.