Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.62 |
| ▸ | ABAT | P80404 | 1/20 | 0.62 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.53 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622086 | 0.93 | ALDH5A1 (0.56) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL99723 | 0.85 | ALDH5A1 (0.58) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL16958918 | 0.83 | MAPT (0.55) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL16960708 | 0.83 | ALDH1A1 (0.55) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL1466944 | 0.82 | ALDH5A1 (0.69) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL31484716 | 0.82 | ALDH5A1 (0.69) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL740884 | 0.79 | MAPT (0.62) | ALDH5A1ABATALDH1A1MAPTKDM4E | |
| SCHEMBL3068948 | 0.79 | MAPT (0.62) | ALDH5A1ABATALDH1A1MAPTKDM4E | |
| SCHEMBL740207 | 0.79 | MAPT (0.62) | ALDH5A1ABATALDH1A1MAPTKDM4E | |
| SCHEMBL10971487 | 0.78 | ALDH5A1 (0.65) | ALDH5A1ABATVCAM1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853726-B | Colorimetric probe for detecting cyanide ions and preparation method and application thereof | 上海应用技术大学 | 2023-05-30 | — | — | CN | claimed |
| CN-114853726-A | Colorimetric probe for cyanide ion detection and preparation method and application thereof | 上海应用技术大学 | 2022-08-05 | — | — | CN | claimed |
| CN-109897006-B | Preparation method of mesosulfuron-methyl | 扬州大学 | 2022-06-03 | — | — | CN | claimed |
| CN-113072552-A | Beta-carboline GSK3 beta/DYRK 1A dual inhibitor, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2021-07-06 | — | — | CN | claimed |
| US-12497377-B2 | Tricyclic spiro compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-12-16 | — | — | US | disclosed |
| WO-2025103477-A1 | COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2025-05-22 | — | — | WO | disclosed |
| CN-113631168-B | GPR35 modulators | 普罗米修斯生物科学公司 | 2024-11-19 | — | — | CN | disclosed |
| EP-3914256-B1 | GPR35 MODULATORS | PROMETHEUS BIOSCIENCES INC (US) | 2024-05-29 | — | — | EP | disclosed |
| CN-117623931-A | Preparation method of safe and environment-friendly mono-nitro aromatic hydrocarbon | 清源创新实验室 | 2024-03-01 | — | — | CN | disclosed |
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2023-11-09 | — | — | US | disclosed |
| US-20230348394-A1 | COMPOSITIONS AND METHODS FOR TREATING MUSCULAR DYSTROPHIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-11-02 | — | — | US | disclosed |
| US-11773101-B2 | GPR35 modulators | PROMETHEUS BIOSCIENCES, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| WO-2001083484-A1 | PYRANO, PIPERIDINO, AND THIOPYRANO COMPOUNDS AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2001-11-08 | — | — | WO | disclosed |
| WO-2001083480-A2 | DIHYDROPYRIDINE COMPOUNDS AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2001-11-08 | — | — | WO | disclosed |
| WO-2001066544-A2 | TRICYCLIC DIHYDROPYRAZOLONE AND TRICYCLIC DIHYDROISOXAZOLONE POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | disclosed |
| US-6162918-A | Xanthene and acridine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2000-12-19 | — | — | US | disclosed |
| US-5969139-A | INHIBITORS OF HERPES SIMPLEX VIRUS THYMIDINE KINASE | HOFFMANN-LA ROCHE INC. (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0823426-A1 | Xanthene and acridine derivatives and their use | F. HOFFMANN-LA ROCHE AG (CH) | 1998-02-11 | — | — | EP | disclosed |
| EP-0699196-A1 | CARBAZOLE DERIVATIVES WITH 17,20-LYASE-INHIBITING ACTIVITY | GLAXO GROUP LIMITED (GB) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994027989-A1 | CARBAZOLE DERIVATIVES WITH 17,20-LYASE-INHIBITING ACTIVITY | GLAXO GROUP LIMITED (GB) | 1994-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | HDAC7, ACHE, BRDT | ALDH5A1 534/4885ABAT 20/4885VCAM1 4878/4885 |
| US-11773101-B2 | GPR35 modulators | GPR35, GPR55, GPR65 | ALDH5A1 2069/4885ABAT 1254/4885VCAM1 1263/4885 |
| US-20230348394-A1 | COMPOSITIONS AND METHODS FOR TREATING MUSCULAR DYSTROPHIES | TNNC1, PYGM, GYS1 | ALDH5A1 1562/4885ABAT 420/4885VCAM1 2819/4885 |
| US-12497377-B2 | Tricyclic spiro compound | PTGER4, PTGER1, PTGER3 | ALDH5A1 1543/4885ABAT 4303/4885VCAM1 2811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.