SCHEMBL10053115

SCHEMBL10053115

CC(C)c1ccc(Cl)cc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.59
SLC6A2 P23975 2/20 0.59
TRPA1 O75762 1/20 0.59
CHRM1 P11229 1/20 0.59
ADRA1A P35348 1/20 0.59
HTR2B P41595 1/20 0.59
GABRA1 P14867 2/20 0.52
GABRB1 P18505 1/20 0.52
HSD17B10 Q99714 4/20 0.50
ALDH1A1 P00352 4/20 0.50
CYP3A4 P08684 3/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
GABRB2 P47870 1/20 0.48
HTT P42858 4/20 0.47
TP53 P04637 1/20 0.47
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
MAPT P10636 3/20 0.46
MAPK1 P28482 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51572 0.86 ALDH1A1 (0.50) LMNASLC6A2TRPA1CHRM1ADRA1A
SCHEMBL815863 0.82 MEN1 (0.59) LMNASLC6A2TRPA1CHRM1ADRA1A
SCHEMBL12197660 0.78 GABRA1 (0.52) LMNASLC6A2TRPA1CHRM1ADRA1A
SCHEMBL27697380 0.78 PTGS2 (0.45) LMNAHTR2BHSD17B10ALDH1A1CYP3A4
SCHEMBL19996996 0.77 LMNA (0.50) LMNASLC6A2TRPA1CHRM1ADRA1A
SCHEMBL10702604 0.76 LMNA (0.72) LMNASLC6A2TRPA1CHRM1ADRA1A
SCHEMBL383417 0.76 LMNA (0.64) LMNASLC6A2TRPA1CHRM1ADRA1A
SCHEMBL31045502 0.76 LMNA (0.68) LMNAGABRA1GABRB1HSD17B10ALDH1A1
SCHEMBL16528005 0.76 LMNA (0.64) LMNASLC6A2TRPA1CHRM1ADRA1A
SCHEMBL29446964 0.76 LMNA (0.64) LMNASLC6A2TRPA1CHRM1ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 CN claimed
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
US-20240206470-A1 VOLATILE APPLICATIONS AGAINST PATHOGENS AGROFRESH INC (US) 2024-06-27 US disclosed
US-20240206470-A1 VOLATILE APPLICATIONS AGAINST PATHOGENS AGROFRESH INC (US) 2024-06-27 US disclosed
CN-112679635-B Preparation method of supported metallocene catalyst and catalyst prepared by preparation method 中国石油化工股份有限公司 2024-03-26 CN disclosed
US-11771089-B2 Large-scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness AGROFRESH INC. (US) 2023-10-03 US disclosed
US-11771089-B2 Large-scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness AGROFRESH INC. (US) 2023-10-03 US disclosed
US-11766043-B2 Vaporized administration of pesticides AGROFRESH INC. (US) 2023-09-26 US disclosed
US-11766043-B2 Vaporized administration of pesticides AGROFRESH INC. (US) 2023-09-26 US disclosed
US-20230227426-A1 PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE AKEBIA THERAPEUTICS, INC. (US) 2023-07-20 US disclosed
US-20150223466-A1 VOLATILE APPLICATIONS AGAINST PATHOGENS DOW AGROSCIENCES LLC (US) 2015-08-13 US disclosed
US-20140349853-A1 USE OF BENZOXABOROLES AS VOLATILE ANTIMICROBIAL AGENTS ON MEATS, PLANTS, OR PLANT PARTS DOW AGROSCIENCES LLC (US) 2014-11-27 US disclosed
US-20140221312-A1 USE OF BENZOXABOROLES AS VOLATILE ANTIMICROBIAL AGENTS ON MEATS, PLANTS, OR PLANT PARTS DOW AGROSCIENCES LLC (US) 2014-08-07 US disclosed
US-8377639-B2 Compounds for modulating RNA binding proteins and uses therefor UNIVERSITY OF MASSACHUSETTS (US) 2013-02-19 US disclosed
US-8106031-B2 Hydrolytically-resistant boron-containing therapeutics and methods of use ANACOR PHARMACEUTICALS, INC. (US) 2012-01-31 US disclosed
EP-2305651-A1 2,3,6-trisubstituted-4-pyrimidone derivatives Mitsubishi Tanabe Pharma Corporation (JP) 2011-04-06 EP disclosed
US-20110065704-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-03-17 US disclosed
US-20070265226-A1 Hydrolytically-Resistant Boron-Containing Therapeutics And Methods Of Use ANACOR PHARMACEUTICALS (US) 2007-11-15 US disclosed
US-20070049603-A1 Raf inhibitor compounds and methods of use thereof ARRAY BIOPHARMA INC. 2007-03-01 US disclosed
US-20070049603-A1 Raf inhibitor compounds and methods of use thereof ARRAY BIOPHARMA INC. 2007-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070049603-A1 Raf inhibitor compounds and methods of use thereof BRAF, RAF1, ARAF LMNA 1333/4885SLC6A2 3580/4885TRPA1 4672/4885
US-20140349853-A1 USE OF BENZOXABOROLES AS VOLATILE ANTIMICROBIAL AGENTS ON MEATS, PLANTS, OR PLANT PARTS OXA1L, BROX, BOLA2; BOLA2B LMNA 2341/4885SLC6A2 4385/4885TRPA1 981/4885
US-20240206470-A1 VOLATILE APPLICATIONS AGAINST PATHOGENS OXA1L, VAPB, TIAL1 LMNA 2510/4885SLC6A2 1799/4885TRPA1 37/4885
US-20140221312-A1 USE OF BENZOXABOROLES AS VOLATILE ANTIMICROBIAL AGENTS ON MEATS, PLANTS, OR PLANT PARTS OXA1L, BROX, BOLA2; BOLA2B LMNA 2341/4885SLC6A2 4385/4885TRPA1 981/4885
US-11766043-B2 Vaporized administration of pesticides GPX4, CAT, PRDX2 LMNA 4168/4885SLC6A2 2749/4885TRPA1 539/4885
US-20230227426-A1 PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE HIF1AN, EGLN3, PHF20 LMNA 4082/4885SLC6A2 4331/4885TRPA1 4469/4885
US-20150223466-A1 VOLATILE APPLICATIONS AGAINST PATHOGENS OXA1L, TIAL1, VAPB LMNA 3005/4885SLC6A2 2623/4885TRPA1 34/4885
US-11771089-B2 Large-scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness TAS2R10, FOSB, TMBIM6 LMNA 701/4885SLC6A2 3388/4885TRPA1 629/4885
US-20110065704-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR TIA1, ZFP3, RBM3 LMNA 2017/4885SLC6A2 4598/4885TRPA1 754/4885
US-20070265226-A1 Hydrolytically-Resistant Boron-Containing Therapeutics And Methods Of Use GAA, BTD, MANBA LMNA 1041/4885SLC6A2 3224/4885TRPA1 4871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.