SCHEMBL1005703

SCHEMBL1005703

[O]C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.43
CA2 P00918 3/20 0.39
CA1 P00915 2/20 0.36
MMP1 P03956 2/20 0.36
MMP2 P08253 2/20 0.36
MMP9 P14780 2/20 0.36
MMP8 P22894 2/20 0.36
MMP13 P45452 2/20 0.36
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1006161 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1006074 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1005294 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1006397 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1006453 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1007393 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL330805 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL843600 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL910572 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1007075 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111492497-B Charge-transporting varnish and charge-transporting film 日产化学株式会社 2023-05-26 CN disclosed
US-20200339825-A1 CHARGE TRANSPORTING VARNISH AND CHARGE TRANSPORTING THIN FILM NISSAN CHEMICAL CORPORATION (JP) 2020-10-29 US disclosed
EP-3731291-A1 CHARGE-TRANSPORTING VARNISH AND CHARGE-TRANSPORTING THIN FILM Nissan Chemical Corporation (JP) 2020-10-28 EP disclosed
EP-3059235-B1 TETRAZOLINONE DERIVATIVES AND THEIR USE FOR CONTROLLING PESTS SUMITOMO CHEMICAL CO (JP) 2020-10-28 EP disclosed
CN-111492497-A Charge-transporting varnish and charge-transporting film 日产化学株式会社 2020-08-04 CN disclosed
EP-3260458-B1 POLYCYCLIC AROMATIC COMPOUND UNIV KYOTO (JP) 2019-09-18 EP disclosed
US-20190214575-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC CORPORATION (JP) 2019-07-11 US disclosed
US-10085450-B2 Tetrazolinone compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-10-02 US disclosed
US-20180047913-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC CORPORATION (JP) 2018-02-15 US disclosed
EP-3260458-A1 POLYCYCLIC AROMATIC COMPOUND KYOTO UNIVERSITY (JP) 2017-12-27 EP disclosed
US-20130066070-A1 PROCESS FOR PRODUCING ESTER COMPOUND WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2013-03-14 US disclosed
US-8318964-B2 Process for producing ester compound WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2012-11-27 US disclosed
US-8298444-B2 Oligoaniline compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-10-30 US disclosed
US-20110195355-A1 CHARGE-TRANSPORTING VARNISHES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-08-11 US disclosed
EP-2339659-A1 CHARGE-TRANSPORTING VARNISHES Nissan Chemical Industries, Ltd. (JP) 2011-06-29 EP disclosed
EP-2272817-A1 PAI-1 INHIBITOR Institute of Medicinal Molecular Design, Inc. (JP) 2011-01-12 EP disclosed
US-20100324314-A1 PROCESS FOR PRODUCING ESTER COMPOUND WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-12-23 US disclosed
US-20100230639-A1 OLIGOANILINE COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-09-16 US disclosed
EP-2143708-A1 OLIGOANILINE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2010-01-13 EP disclosed
US-20090312315-A1 PAI-1 INHIBITOR INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2009-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130066070-A1 PROCESS FOR PRODUCING ESTER COMPOUND ADH1C, ADH5, ADH1A LMNA 2262/4885THRB 2198/4885CA2 892/4885
US-10085450-B2 Tetrazolinone compound and use thereof ROS1, TCOF1, RPS20 LMNA 4241/4885THRB 281/4885CA2 1403/4885
US-20180047913-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE L1CAM, VDAC1, VDAC2 LMNA 2374/4885THRB 4478/4885CA2 1872/4885
US-20190214575-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE L1CAM, VDAC1, VDAC2 LMNA 2374/4885THRB 4478/4885CA2 1872/4885
US-20090312315-A1 PAI-1 INHIBITOR SERPINC1, SERPINE1, SERPINH1 LMNA 590/4885THRB 1211/4885CA2 2722/4885
US-20100324314-A1 PROCESS FOR PRODUCING ESTER COMPOUND ADH1C, ADH5, ADH1A LMNA 2434/4885THRB 2104/4885CA2 742/4885
US-20100230639-A1 OLIGOANILINE COMPOUND OPRD1, NSD1, OCIAD1 LMNA 3099/4885THRB 997/4885CA2 4196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.