Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | NCF1 | P14598 | 2/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2504209 | 0.86 | KDM4E (0.68) | MAPTCYP3A4KDM4ELOXL2NCF1 | |
| Hydrochloric Acid SCHEMBL30925271 | 0.83 | KDM4E (0.74) | MAPTCYP3A4KDM4ELOXL2NCF1 | |
| SCHEMBL291602 | 0.80 | ALDH1A1 (0.52) | MAPTCYP3A4KDM4ETSHRAPP | |
| SCHEMBL19373099 | 0.80 | APP (0.40) | MAPTCYP3A4KDM4ELOXL2TSHR | |
| SCHEMBL13184538 | 0.78 | KDM4E (0.59) | MAPTCYP3A4KDM4ELOXL2NCF1 | |
| SCHEMBL28371614 | 0.77 | APP (0.42) | MAPTCYP3A4KDM4ELOXL2TSHR | |
| SCHEMBL153943 | 0.76 | TSHR (0.67) | MAPTCYP3A4TSHRAPPALDH1A1 | |
| SCHEMBL2720527 | 0.76 | HPGD (0.48) | MAPTTSHRAPPALDH1A1HSD17B10 | |
| SCHEMBL296509 | 0.76 | MAPT (0.56) | MAPTCYP3A4KDM4ELOXL2NCF1 | |
| SCHEMBL2848915 | 0.76 | MAPT (0.56) | MAPTCYP3A4KDM4ELOXL2NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000813-A1 | COMPOUND FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE | INTERVET INC. (US) | 2023-01-05 | — | — | US | disclosed |
| EP-4108675-A1 | PREPARATION AND USE OF IMMUNOSTIMULATORY COUPLING COMPLEX WHICH IS DELIVERED AND ACTIVATED IN TARGETED MANNER | Yafei Shanghai Biolog Medicine Science & Technology Co., Ltd. (CN) | 2022-12-28 | — | — | EP | disclosed |
| US-20210347730-A1 | COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE | INTERVET INC. (US) | 2021-11-11 | — | — | US | disclosed |
| US-20210292284-A1 | COMPOUNDS USEFUL FOR THE TREATMENT OF INFECTION WITH MANNHEIMIA HAEMOLYTICA OR HISTOPHILUS SOMNI | INTERVET INC. (US) | 2021-09-23 | — | — | US | disclosed |
| US-11034650-B2 | Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection | INTERVET INC. (US) | 2021-06-15 | — | — | US | disclosed |
| EP-3693022-A2 | COX-2-TARGETING, PLATINUM-CONTAINING CONJUGATES AND THEIR USE IN THE TREATMENT OF TUMORS AND CANCERS | Reiley Pharmaceuticals, Inc. (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-3666788-A1 | HEMIASTERLIN DERIVATIVES AND ANTIBODY-DRUG CONJUGATES INCLUDING SAME | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |
| US-20200085779-A1 | Compounds for the Treatment of Bovine or Swine Respiratory Disease | INTERVET INC. (US) | 2020-03-19 | — | — | US | disclosed |
| US-20190352256-A1 | Compounds Useful for Treating a Mannheimia Haemolytica or Histophilus Somni Infection | INTERVET INC. (US) | 2019-11-21 | — | — | US | disclosed |
| WO-2019010231-A1 | PROCHELATORS AS TARGETED PRODRUGS FOR PROSTATE CANCER AND METHODS OF MAKING AND USING SAME | DUKE UNIVERSITY (US) | 2019-01-10 | — | — | WO | disclosed |
| US-20160200752-A1 | COX-2-TARGETING, PLATINUM-CONTAINING CONJUGATES AND THEIR USE IN THE TREATMENT OF TUMORS AND CANCERS | Reiley Pharmaceuticals, Inc. | 2016-07-14 | — | — | US | disclosed |
| EP-2201071-B1 | REACTIVE DYES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | HUNTSMAN ADV MAT SWITZERLAND (CH) | 2012-01-18 | — | — | EP | disclosed |
| US-7905928-B2 | Reactive dyes, processes for their preparation and their use | HUNTSMAN INTERNATIONAL LLC (US) | 2011-03-15 | — | — | US | disclosed |
| US-7905928-B2 | Reactive dyes, processes for their preparation and their use | HUNTSMAN INTERNATIONAL LLC (US) | 2011-03-15 | — | — | US | disclosed |
| US-20110052625-A1 | COMPOSITIONS AND METHODS FOR TREATING DIABETES USING LISOFYLLINE ANALOGS AND ISLET NEOGENESIS ASSOCIATED PEPTIDE | DIAKINE THERAPEUTICS, INC. (US) | 2011-03-03 | — | — | US | disclosed |
| US-20100251490-A1 | REACTIVE DYES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | HUNTSMAN INTERNATIONAL LLC (US) | 2010-10-07 | — | — | US | disclosed |
| US-20100251490-A1 | REACTIVE DYES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | HUNTSMAN INTERNATIONAL LLC (US) | 2010-10-07 | — | — | US | disclosed |
| WO-2009053238-A2 | REACTIVE DYES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2009-04-30 | — | — | WO | disclosed |
| WO-2007077129-A2 | REACTIVE DYES, A PROCESS FOR THEIR PREPARATION AND THEIR USE | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2007-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200752-A1 | COX-2-TARGETING, PLATINUM-CONTAINING CONJUGATES AND THEIR USE IN THE TREATMENT OF TUMORS AND CANCERS | PTGS2, PTGES2, TOP2A | MAPT 4235/4885CYP3A4 3696/4885KDM4E 3276/4885 |
| US-11034650-B2 | Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection | HEXD, SORD, SDHA | MAPT 3946/4885CYP3A4 875/4885KDM4E 4069/4885 |
| US-20210347730-A1 | COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE | PIGS, BTD, PPARD | MAPT 2194/4885CYP3A4 1430/4885KDM4E 4510/4885 |
| US-20210292284-A1 | COMPOUNDS USEFUL FOR THE TREATMENT OF INFECTION WITH MANNHEIMIA HAEMOLYTICA OR HISTOPHILUS SOMNI | SORD, HEXD, SDHA | MAPT 4092/4885CYP3A4 1092/4885KDM4E 3794/4885 |
| US-20110052625-A1 | COMPOSITIONS AND METHODS FOR TREATING DIABETES USING LISOFYLLINE ANALOGS AND ISLET NEOGENESIS ASSOCIATED PEPTIDE | IAPP, LITAF, IGF2BP1 | MAPT 4124/4885CYP3A4 4833/4885KDM4E 3689/4885 |
| US-20100251490-A1 | REACTIVE DYES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | QSOX1, SCO2, CBR3 | MAPT 4758/4885CYP3A4 409/4885KDM4E 3021/4885 |
| US-20190352256-A1 | Compounds Useful for Treating a Mannheimia Haemolytica or Histophilus Somni Infection | HEXD, SORD, SDHA | MAPT 3946/4885CYP3A4 875/4885KDM4E 4069/4885 |
| US-20230000813-A1 | COMPOUND FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE | PIGS, BTD, BRD1 | MAPT 1823/4885CYP3A4 2376/4885KDM4E 4293/4885 |
| US-20200085779-A1 | Compounds for the Treatment of Bovine or Swine Respiratory Disease | PIGS, BTD, PPARD | MAPT 2161/4885CYP3A4 1989/4885KDM4E 4185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.