Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | EIF2S1 | P05198 | 1/20 | 0.32 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.32 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782139 | 0.94 | DHODH (0.33) | EPHX2CAPN1DHODHRECQLTRPV1 | |
| SCHEMBL10140194 | 0.92 | EPHX2 (0.35) | EPHX2TRPV1MALT1NPC1RAB9A | |
| SCHEMBL10140160 | 0.89 | CARM1 (0.37) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28498417 | 0.87 | DGAT2 (0.32) | DHODHMALT1 | |
| SCHEMBL782239 | 0.86 | EPHX2 (0.35) | EPHX2DHODHTRPV1MALT1ALDH1A1 | |
| SCHEMBL10140185 | 0.86 | RECQL (0.36) | CAPN1RECQLKMT2ATRPV1MALT1 | |
| SCHEMBL12574960 | 0.85 | DHODH (0.35) | EPHX2DHODHTRPV1MALT1 | |
| SCHEMBL31060020 | 0.85 | SLC2A1 (0.36) | EPHX2DHODHTRPV1MALT1RAB9A | |
| SCHEMBL12117068 | 0.85 | WDR5 (0.33) | CAPN1DHODHMALT1EIF2S1EIF2AK3 | |
| SCHEMBL10140172 | 0.84 | DHODH (0.38) | CAPN1DHODHRECQLKMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949482-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-20170071205-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-03-16 | — | — | US | disclosed |
| US-9538755-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2017-01-10 | — | — | US | disclosed |
| US-20160302414-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2016-10-20 | — | — | US | disclosed |
| US-9282743-B2 | Chemical compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-15 | — | — | US | disclosed |
| US-9096525-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140051736-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2014-02-20 | — | — | US | disclosed |
| US-8536089-B2 | For controlling phytopathogenic diseases; synergistic | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-17 | — | — | US | disclosed |
| US-20130210625-A1 | SPIROHETEROCYCLIC PYRROLIDINE DERIVATIVES BASED PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-15 | — | — | US | disclosed |
| US-8124567-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124566-B2 | Synergistic fungicidal compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20080076664-A1 | Fungicidal Compositions | SYNGENTA CROP PROTECTION, INC. | 2008-03-27 | — | — | US | disclosed |
| US-20080070785-A1 | For controlling phytopathogenic diseases; synergistic | SYNGENTA CROP PROTECTION, INC. (US) | 2008-03-20 | — | — | US | disclosed |
| US-20070265267-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, INC. (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070244121-A1 | Synergistic Fungicidal Compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051736-A1 | FUNGICIDAL COMPOSITIONS | PIK3C3, CYP51A1, CYP1B1 | EPHX2 838/4885CAPN1 965/4885DHODH 874/4885 |
| US-20130210625-A1 | SPIROHETEROCYCLIC PYRROLIDINE DERIVATIVES BASED PESTICIDES | DDT, PYCR1, PKD2 | EPHX2 1113/4885CAPN1 249/4885DHODH 248/4885 |
| US-20160302414-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, CASP3 | EPHX2 703/4885CAPN1 2016/4885DHODH 1693/4885 |
| US-20070265267-A1 | FUNGICIDAL COMPOSITIONS | CRY1, ERG28, DDT | EPHX2 2443/4885CAPN1 2292/4885DHODH 2433/4885 |
| US-20070244121-A1 | Synergistic Fungicidal Compositions | DDT, CRY1, HCN1 | EPHX2 2380/4885CAPN1 2102/4885DHODH 1980/4885 |
| US-20080070785-A1 | For controlling phytopathogenic diseases; synergistic | BROX, EPM2A, MANBA | EPHX2 916/4885CAPN1 865/4885DHODH 2383/4885 |
| US-20170071205-A1 | FUNGICIDAL COMPOSITIONS | PIK3C3, CYP51A1, CYP1B1 | EPHX2 838/4885CAPN1 965/4885DHODH 874/4885 |
| US-20080076664-A1 | Fungicidal Compositions | AKR7A2, CYP51A1, TUBA3C | EPHX2 1361/4885CAPN1 2235/4885DHODH 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.