Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9394499 | 0.93 | PTGS1 (0.47) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL4378113 | 0.87 | NPC1 (0.49) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL4378115 | 0.87 | NPC1 (0.49) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| Hydrogen Peroxide SCHEMBL9581174 | 0.86 | PTGS1 (0.64) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL1131597 | 0.86 | PTGS1 (0.56) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL5174938 | 0.83 | PTGS1 (0.54) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL3456644 | 0.81 | EPHX2 (0.46) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL114824 | 0.80 | PTGS1 (0.48) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL1977984 | 0.80 | PTGS2 (0.58) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL4495707 | 0.80 | TAAR1 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423184-B2 | Method of making carbonyl compounds | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-09-09 | — | — | US | claimed |
| EP-1934162-A2 | METHOD OF MAKING BENZYLATED PHENOLS | General Electric Company (US) | 2008-06-25 | — | — | EP | claimed |
| WO-2007027375-A2 | METHOD OF MAKING BENZYLATED PHENOLS | GENERAL ELECTRIC COMPANY (US) | 2007-03-08 | — | — | WO | claimed |
| US-20070049767-A1 | Method of making carbonyl compounds | SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) | 2007-03-01 | — | — | US | claimed |
| JP-5163223-A | — | — | None | — | — | JP | disclosed |
| US-20240239786-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CANCER | YALE UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
| US-20240216361-A1 | ROR-GAMMA MODULATORS | ESCALIER BIOSCIENCES B V (US) | 2024-07-04 | — | — | US | disclosed |
| US-11911751-B2 | Catalyst compositions for hydroformylation and methods of use thereof | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912786-B2 | Inhibitor of apoptosis protein (IAP) antagonists | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-27 | — | — | US | disclosed |
| US-20240025914-A1 | FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE | AKARNA THERAPEUTICS LTD (GB) | 2024-01-25 | — | — | US | disclosed |
| US-20240018089-A1 | THERAPEUTIC DNP DERIVATIVES AND METHODS USING SAME | UNIV YALE (US) | 2024-01-18 | — | — | US | disclosed |
| US-11873312-B2 | Transcriptome in vivo analysis (TIVA) and transcriptome in situ analysis (TISA) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2024-01-16 | — | — | US | disclosed |
| US-4935240-A | Benzoylaminophenoxybutanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| EP-0294035-A2 | Benzoylaminophenoxybutanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-12-07 | — | — | EP | disclosed |
| EP-0244632-A2 | Tube bundle reactor, its use in exothermal organic reactions and process for the preparation of ketones and aldehydes | BASF Aktiengesellschaft (DE) | 1987-11-11 | — | — | EP | disclosed |
| US-4683244-A | Sebosuppressive cosmetic preparations containing alkoxy or alkylbenzyloxy benzoic acids or their salts | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1987-07-28 | — | — | US | disclosed |
| EP-0186255-A2 | Process for preparing benzyl substituted phenols, dibenzylphenolic compounds, and the antioxidant use of such phenols | ETHYL CORPORATION (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4514577-A | ANTIOXIDANTS | ETHYL CORPORATION (US) | 1985-04-30 | — | — | US | disclosed |
| US-4224254-A | OXIDATION OF AROMATIC ALCOHOLS, SILVER CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1980-09-23 | — | — | US | disclosed |
| EP-0004881-A2 | Process for the preparation of aromatic and araliphatic aldehydes | BASF Aktiengesellschaft (DE) | 1979-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018089-A1 | THERAPEUTIC DNP DERIVATIVES AND METHODS USING SAME | DNPEP, NQO1, DNPH1 | PTGS1 751/4885PTGS2 921/4885ALOX5 1195/4885 |
| US-11873312-B2 | Transcriptome in vivo analysis (TIVA) and transcriptome in situ analysis (TISA) | RNMT, RNGTT, NSUN2 | PTGS1 4480/4885PTGS2 4447/4885ALOX5 3668/4885 |
| US-20240216361-A1 | ROR-GAMMA MODULATORS | RORB, RORC, RORA | PTGS1 1104/4885PTGS2 1274/4885ALOX5 756/4885 |
| US-20070049767-A1 | Method of making carbonyl compounds | SOD1, CAT, MT-CO2 | PTGS1 1003/4885PTGS2 316/4885ALOX5 401/4885 |
| US-20240239786-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CANCER | BRCA1, RAD51, PARP3 | PTGS1 662/4885PTGS2 1350/4885ALOX5 459/4885 |
| US-20240025914-A1 | FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE | VHL, BRDT, PAICS | PTGS1 3856/4885PTGS2 3278/4885ALOX5 2906/4885 |
| US-11912786-B2 | Inhibitor of apoptosis protein (IAP) antagonists | API5, XIAP, BIRC5 | PTGS1 2406/4885PTGS2 3029/4885ALOX5 4105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.