SCHEMBL10282965

SCHEMBL10282965

CCC(Oc1ccc(C(NC)C(F)(F)F)cc1)Oc1ccc(C(NC)C(F)(F)F)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 9/20 0.37
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
LMNA P02545 4/20 0.37
SLC6A2 P23975 4/20 0.37
SLC6A3 Q01959 4/20 0.37
NPC1 O15118 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C19 P33261 2/20 0.37
MTOR P42345 2/20 0.37
RAB9A P51151 2/20 0.37
CYP3A4 P08684 2/20 0.37
HTR2C P28335 2/20 0.37
HRH3 Q9Y5N1 2/20 0.37
KCNK2 O95069 2/20 0.37
KCNH2 Q12809 2/20 0.37
CACNA1C Q13936 2/20 0.37
KDM4E B2RXH2 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10279764 0.79 CTSL (0.41) SLC6A4MEN1KMT2ALMNASLC6A2
SCHEMBL10279734 0.78 ALDH1A1 (0.46) KMT2ALMNANPC1RAB9AKDM4E
SCHEMBL12197655 0.72 PTPN1 (0.38) ALDH1A1CTSLCTSSCTSK
SCHEMBL13911344 0.72 CTSL (0.38) SLC6A4MEN1KMT2ALMNASLC6A2
SCHEMBL25698227 0.71 CTSL (0.41) SLC6A4KMT2ALMNAACHEHTT
SCHEMBL1421212 0.70 OPRK1 (0.45) MEN1KMT2ALMNACYP2D6CYP2C19
SCHEMBL12797626 0.70 OPRK1 (0.45) MEN1KMT2ALMNACYP2D6CYP2C19
SCHEMBL8285031 0.70 CTSK (0.43) SLC6A4SLC6A2SLC6A3CYP2D6CYP3A4
SCHEMBL22016509 0.70 KIF11 (0.44) SLC6A4MEN1KMT2ALMNASLC6A2
SCHEMBL21549470 0.70 ALDH1A1 (0.34) MEN1KMT2ANPC1RAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7928262-B2 Onium salts, oxime sulfonates and sulfonyloxyimides derived from these sulfonium salts are effective photoacid generators in chemically amplified resist compositions; sensitive to high-energy radiation SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-04-19 US disclosed
US-7919226-B2 Sulfonate salts and derivatives, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-04-05 US disclosed
US-7670751-B2 Photoacid generator, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-03-02 US disclosed
US-7569324-B2 Sulfonate salts and derivatives, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-04 US disclosed
US-7556909-B2 Sulfonate salts and derivatives, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-07-07 US disclosed
US-7531290-B2 Sulfonate salts and derivatives, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-05-12 US disclosed
US-7527912-B2 Photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-05-05 US disclosed
US-20090061358-A1 NOVEL PHOTOACID GENERATOR, RESIST COMPOSITION, AND PATTERNING PROCESS PROXIMAL SYSTEMS CORPORATION 2009-03-05 US disclosed
US-20080318160-A1 Novel sulfonate salts and derivatives, photoacid generators, resist compositions, and patterning process RITTAL GMBH & CO. KG (DE) 2008-12-25 US disclosed
US-20080124656-A1 NOVEL SULFONATE SALTS AND DERIVATIVES, PHOTOACID GENERATORS, RESIST COMPOSITIONS, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-05-29 US disclosed
US-20080085469-A1 Novel photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. 2008-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090061358-A1 NOVEL PHOTOACID GENERATOR, RESIST COMPOSITION, AND PATTERNING PROCESS RER1, CRY1, CYP21A2 SLC6A4 2935/4885MEN1 718/4885KMT2A 3509/4885
US-20080124656-A1 NOVEL SULFONATE SALTS AND DERIVATIVES, PHOTOACID GENERATORS, RESIST COMPOSITIONS, AND PATTERNING PROCESS HCN3, ASIC3, HCN4 SLC6A4 1352/4885MEN1 2210/4885KMT2A 147/4885
US-20080085469-A1 Novel photoacid generators, resist compositions, and patterning process RER1, SCO2, ASIC3 SLC6A4 2541/4885MEN1 3960/4885KMT2A 1964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.