SCHEMBL1031052

SCHEMBL1031052

CC(COC(=O)c1ccccc1O)OCC(C)OCC(O)CO

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 7/20 0.53
ADRB1 P08588 7/20 0.53
ADRB3 P13945 7/20 0.53
ALDH1A1 P00352 4/20 0.51
TSHR P16473 2/20 0.51
LMNA P02545 2/20 0.48
TDP1 Q9NUW8 3/20 0.47
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
HTT P42858 2/20 0.42
KMT2A Q03164 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 1/20 0.38
TP53 P04637 1/20 0.38
NPY1R P25929 1/20 0.38
NPY2R P49146 1/20 0.38
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39481 0.86 ALDH1A1 (0.57) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL29613210 0.86 ADRB2 (0.63) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL446204 0.86 ADRB2 (0.63) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL17629572 0.86 ADRB2 (0.63) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL17629569 0.86 ADRB2 (0.63) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL6062484 0.85 ALDH1A1 (0.55) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL6062826 0.85 ALDH1A1 (0.55) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL6062474 0.85 ALDH1A1 (0.55) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL30163245 0.80 ALDH1A1 (0.79) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL14763796 0.80 ALDH1A1 (0.79) ADRB2ADRB1ADRB3ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238303-A1 LARGE-CONDUCTANCE POTASSIUM CHANNEL MODULATORS, COMPOSITIONS THEREOF, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF ENALARE THERAPEUTICS INC (US) 2024-07-18 US disclosed
US-20240226007-A1 NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) COMPOSITIONS, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF Sovida Solutions Ltd. (GB) 2024-07-11 US disclosed
EP-4333807-A1 NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) COMPOSITIONS, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF Sovida Solutions Ltd. (GB) 2024-03-13 EP disclosed
EP-4333852-A1 LARGE-CONDUCTANCE POTASSIUM CHANNEL MODULATORS, COMPOSITIONS THEREOF, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF Enalare Therapeutics Inc. (US) 2024-03-13 EP disclosed
EP-3870261-B1 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT BIORA THERAPEUTICS INC (US) 2024-01-31 EP disclosed
EP-4309722-A2 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT Biora Therapeutics, Inc. (US) 2024-01-24 EP disclosed
US-20230414624-A1 METHODS OF TREATING NEUROLOGICAL VENTILATORY INSUFFICIENCY ENALARE THERAPEUTICS INC (US) 2023-12-28 US disclosed
US-20230310440-A1 RESPIRATORY STIMULANT NASAL FORMULATIONS ENALARE THERAPEUTICS INC. 2023-10-05 US disclosed
WO-2023192602-A2 RESPIRATORY STIMULANT NASAL FORMULATIONS ENALARE THERAPEUTICS INC. (US) 2023-10-05 WO disclosed
US-11707610-B2 Ingestible device for delivery of therapeutic agent to the gastrointestinal tract BIORA THERAPEUTICS, INC. (US) 2023-07-25 US disclosed
US-20040253310-A1 A opioid matrix is coated with a cellulose mixture layer; controlling the release of opioid, preventing the side effect of immediate release opioid in blood stream; water soluble and water insoluble celluloses; pain treatment EGALET LTD. (GB) 2004-12-16 US disclosed
US-20040234602-A1 Polymer release system EGALET LTD. (GB) 2004-11-25 US disclosed
WO-2004084868-A1 MORPHINE CONTROLLED RELEASE SYSTEM EGALET A/S (DK) 2004-10-07 WO disclosed
WO-2004084869-A1 MATRIX COMPOSITIONS FOR CONTROLLED DELIVERY OF DRUG SUBSTANCES EGALET A/S (DK) 2004-10-07 WO disclosed
EP-1429734-A1 CONTROLLED RELEASE SOLID DISPERSIONS Egalet A/S (DK) 2004-06-23 EP disclosed
EP-1429739-A1 POLYMER RELEASE SYSTEM Egalet A/S (DK) 2004-06-23 EP disclosed
EP-1429744-A1 MORPHINE POLYMER RELEASE SYSTEM Egalet A/S (DK) 2004-06-23 EP disclosed
WO-2003024430-A1 MORPHINE POLYMER RELEASE SYSTEM EGALET A/S (DK) 2003-03-27 WO disclosed
WO-2003024426-A1 CONTROLLED RELEASE SOLID DISPERSIONS EGALET A/S (DK) 2003-03-27 WO disclosed
WO-2003024429-A1 POLYMER RELEASE SYSTEM EGALET A/S (DK) 2003-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11707610-B2 Ingestible device for delivery of therapeutic agent to the gastrointestinal tract MUC1, SLC10A2, FABP2 ADRB2 1556/4885ADRB1 2521/4885ADRB3 2232/4885
US-20230310440-A1 RESPIRATORY STIMULANT NASAL FORMULATIONS ADRA2C, MTNR1B, MTNR1A ADRB2 14/4885ADRB1 12/4885ADRB3 20/4885
US-20240238303-A1 LARGE-CONDUCTANCE POTASSIUM CHANNEL MODULATORS, COMPOSITIONS THEREOF, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF KCNN2, KCNN1, KCNN3 ADRB2 520/4885ADRB1 636/4885ADRB3 553/4885
US-20230414624-A1 METHODS OF TREATING NEUROLOGICAL VENTILATORY INSUFFICIENCY SDHA, NDUFB7, OTC ADRB2 745/4885ADRB1 1060/4885ADRB3 931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.