Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 13/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | MELK | Q14680 | 3/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10324875 | 0.89 | MELK (0.40) | MELKSCDFFAR4 | |
| SCHEMBL10326401 | 0.89 | MELK (0.39) | MELKFFAR4 | |
| SCHEMBL10380728 | 0.69 | FFAR4 (0.43) | DGAT1FFAR4 | |
| SCHEMBL10325542 | 0.69 | GPR119 (0.37) | DGAT1 | |
| SCHEMBL17729168 | 0.69 | IDO1 (0.54) | — | |
| SCHEMBL10380233 | 0.69 | FFAR4 (0.41) | DGAT1KCNH2ADORA2AFFAR4 | |
| SCHEMBL10379959 | 0.69 | DGAT1 (0.47) | DGAT1KCNH2ADORA2AERN1MELK | |
| SCHEMBL10325123 | 0.66 | KDM4E (0.46) | MELK | |
| SCHEMBL1727604 | 0.65 | HTR1A (0.41) | DGAT1KCNH2ADORA2ASCD | |
| SCHEMBL14969291 | 0.64 | ERN1 (0.46) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012096813-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-07-19 | — | — | WO | disclosed |