Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A known ✓ | P04350 | 1/20 | 0.33 |
| ▸ | TUBB known ✓ | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C known ✓ | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B known ✓ | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A known ✓ | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B known ✓ | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 known ✓ | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A known ✓ | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 known ✓ | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E known ✓ | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A known ✓ | Q71U36 | 1/20 | 0.33 |
| ▸ | TUBA1C known ✓ | Q9BQE3 | 1/20 | 0.33 |
| ▸ | TUBB6 known ✓ | Q9BUF5 | 1/20 | 0.33 |
| ▸ | TUBB2B known ✓ | Q9BVA1 | 1/20 | 0.33 |
| ▸ | TUBB1 known ✓ | Q9H4B7 | 1/20 | 0.33 |
| ▸ | DUSP5 | Q16690 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14535575 | 0.78 | KMT2A (0.40) | KMT2AMAPTPOLBKDM4EAPEX1 | |
| SCHEMBL10448372 | 0.76 | CA12 (0.48) | DUSP5KMT2AMAPTPOLBKDM4E | |
| SCHEMBL10448371 | 0.74 | DUSP5 (0.42) | DUSP5KMT2AKDM4ERECQLHTT | |
| SCHEMBL10448375 | 0.74 | DUSP5 (0.42) | DUSP5KMT2AKDM4ERECQLHTT | |
| SCHEMBL10590243 | 0.74 | LMNA (0.55) | DUSP5KMT2AMAPTPOLBKDM4E | |
| SCHEMBL1964224 | 0.71 | DUSP5 (0.50) | DUSP5KMT2AMAPTPOLBKDM4E | |
| SCHEMBL218311 | 0.70 | PTGS2 (0.49) | KMT2AMAPTPOLBKDM4EAPEX1 | |
| SCHEMBL30659810 | 0.70 | PTGS2 (0.49) | KMT2AMAPTPOLBKDM4EAPEX1 | |
| SCHEMBL11333846 | 0.70 | CA12 (0.46) | KMT2AMAPTPOLBKDM4EAPEX1 | |
| SCHEMBL3375499 | 0.70 | DUSP5 (0.49) | DUSP5KMT2AMAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350096-A2 | Bleaching detergent compositions | UNILEVER N.V. (NL) | 1990-01-10 | — | — | EP | disclosed |