Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 known ✓ | P35354 | 8/20 | 0.49 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GGT1 | P19440 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30659810 | 1.00 | PTGS2 (0.49) | PTGS2KDM4EHSD17B10ALDH1A1BLM | |
| Potassium Ion SCHEMBL5180749 | 0.96 | PTGS2 (0.49) | PTGS2KDM4EHSD17B10ALDH1A1BLM | |
| SCHEMBL11759898 | 0.85 | ELANE (0.43) | PTGS2KDM4EHSD17B10ALDH1A1BLM | |
| SCHEMBL6535328 | 0.81 | PTGS2 (0.52) | PTGS2KDM4EHSD17B10ALDH1A1BLM | |
| SCHEMBL3018679 | 0.81 | PTGS2 (0.52) | PTGS2KDM4EHSD17B10ALDH1A1BLM | |
| SCHEMBL29753992 | 0.81 | PTGS2 (0.52) | PTGS2KDM4EHSD17B10ALDH1A1BLM | |
| SCHEMBL8380237 | 0.80 | PTGS2 (0.50) | PTGS2KDM4EHSD17B10ALDH1A1BLM | |
| SCHEMBL11043927 | 0.80 | PTGS2 (0.50) | PTGS2KDM4EHSD17B10ALDH1A1BLM | |
| SCHEMBL8380233 | 0.80 | PTGS2 (0.50) | PTGS2KDM4EHSD17B10ALDH1A1BLM | |
| SCHEMBL14655863 | 0.80 | PTGS2 (0.50) | PTGS2KDM4EHSD17B10ALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777061-A | Epoxy functionalized lithium sulfonyl imide and preparation method and application thereof | 上海交通大学绍兴新能源与分子工程研究院 | 2024-03-29 | — | — | CN | claimed |
| EP-3383503-B1 | HYDROGEN PEROXIDE BOOSTER SYSTEM FOR ENHANCED TEETH WHITENING | COLGATE PALMOLIVE CO (US) | 2022-07-27 | — | — | EP | claimed |
| CN-108430586-B | Hydrogen peroxide booster system for enhanced tooth whitening | 高露洁-棕榄公司 | 2021-07-23 | — | — | CN | claimed |
| US-20200297594-A1 | Hydrogen Peroxide Booster System for Enhanced Teeth Whitening | COLGATE-PALMOLIVE COMPANY (US) | 2020-09-24 | — | — | US | claimed |
| EP-3383243-B1 | PORTABLE STAIN REMOVAL KIT | KONINKLIJKE PHILIPS NV (NL) | 2019-10-23 | — | — | EP | claimed |
| US-20180369087-A1 | Hydrogen Peroxide Booster System for Enhanced Teeth Whitening | COLGATE-PALMOLIVE COMPANY (US) | 2018-12-27 | — | — | US | claimed |
| EP-3383503-A1 | HYDROGEN PEROXIDE BOOSTER SYSTEM FOR ENHANCED TEETH WHITENING | Colgate-Palmolive Company (US) | 2018-10-10 | — | — | EP | claimed |
| WO-2017105455-A1 | HYDROGEN PEROXIDE BOOSTER SYSTEM FOR ENHANCED TEETH WHITENING | COLGATE-PALMOLIVE COMPANY (US) | 2017-06-22 | — | — | WO | claimed |
| US-8431519-B2 | Co-granulates of bleach activator-peroxide compounds | OCI CHEMICAL CORP. (US) | 2013-04-30 | — | — | US | claimed |
| US-20100207062-A1 | CO-GRANULATES OF BLEACH ACTIVATOR-PEROXIDE COMPOUNDS | OCI CHEMICAL CORPORATION (US) | 2010-08-19 | — | — | US | claimed |
| US-5360569-A | Peroxygen bleaches with oxygen transfer agent of isoquinolium compound and forming percarboxylic, percarbonic acid or perimidic acid | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1994-11-01 | — | — | US | claimed |
| EP-0446982-B1 | Low-temperature bleaching compositions | UNILEVER NV (NL) | 1994-10-26 | — | — | EP | claimed |
| EP-0341947-B1 | Enzymatic detergent and bleaching composition | UNILEVER PLC (GB) | 1994-08-31 | — | — | EP | claimed |
| EP-0456032-A1 | Process for bleaching pulps | HOECHST JAPAN LIMITED (JP) | 1991-11-13 | — | — | EP | claimed |
| EP-0446982-A2 | Low-temperature bleaching compositions | UNILEVER N.V. (NL) | 1991-09-18 | — | — | EP | claimed |
| US-5047163-A | Low Temperature Bleaching Composition Containing A Peroxygen Compound, A Sulfonimine Oxygen Transfer Agent Activator And A! Bleach Percursor | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1991-09-10 | — | — | US | claimed |
| EP-0271152-B1 | ENZYMATIC DETERGENT AND BLEACHING COMPOSITION | UNILEVER N.V. (NL) | 1990-07-18 | — | — | EP | claimed |
| EP-0147191-B1 | PERFUME AND COMPOSITIONS CONTAINING PERFUME | UNILEVER N.V. (NL) | 1989-10-04 | — | — | EP | claimed |
| EP-0072098-B1 | BLEACH COMPOSITION | UNILEVER N.V. (NL) | 1985-03-20 | — | — | EP | claimed |
| US-4008167-A | SODIUM PERCARBONATE | KAO SOAP CO., LTD. (JA) | 1977-02-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200297594-A1 | Hydrogen Peroxide Booster System for Enhanced Teeth Whitening | GPX4, GPX1, PRDX3 | PTGS2 724/4885PTGS1 1115/4885KDM4E 3121/4885 |
| US-20180369087-A1 | Hydrogen Peroxide Booster System for Enhanced Teeth Whitening | CAT, GPX4, LPO | PTGS2 1896/4885PTGS1 2165/4885KDM4E 3779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.