Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Pyrogallol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrogallol SCHEMBL4255147 | 0.96 | CA1 (0.52) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL209233 | 0.85 | ALDH1A1 (0.63) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Catechol SCHEMBL27897383 | 0.85 | SMN1; SMN2 (0.53) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL214769 | 0.85 | ALDH1A1 (0.63) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL17768460 | 0.85 | ALDH1A1 (0.71) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL28963965 | 0.82 | ALDH1A1 (0.67) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL29044406 | 0.82 | ALDH1A1 (0.75) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL2882287 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL3367606 | 0.79 | ALDH1A1 (0.71) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL28234833 | 0.79 | CA2 (0.71) | ALDH1A1LMNAHPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240206322-A1 | OPTICAL SEMICONDUCTOR DEVICE, METHOD FOR MANUFACTURING SAME, SOLID-STATE IMAGING DEVICE, AND ELECTRONIC DEVICE | KANEKA CORPORATION (JP) | 2024-06-20 | — | — | US | disclosed |
| US-20230408923-A1 | SUBSTRATE LAMINATE, IMAGE SENSOR, AND METHOD FOR MANUFACTURING SUBSTRATE LAMINATE | KANEKA CORPORATION (JP) | 2023-12-21 | — | — | US | disclosed |
| EP-2679645-B1 | COATING MATERIAL CONTAINING ORGANIC/INORGANIC COMPOSITE, ORGANIC/INORGANIC COMPOSITE FILM AND ANTIREFLECTION MEMBER | ASAHI CHEMICAL IND (JP) | 2021-04-14 | — | — | EP | disclosed |
| EP-3656778-A1 | POLYHEDRAL POLYSILOXANE MODIFIED PRODUCT AND COMPOSITION USING THE MODIFIED PRODUCT | Kaneka Corporation (JP) | 2020-05-27 | — | — | EP | disclosed |
| EP-3378867-B1 | POLYHEDRAL POLYSILOXANE MODIFIED PRODUCT AND COMPOSITION USING THE MODIFIED PRODUCT | KANEKA CORP (JP) | 2020-03-25 | — | — | EP | disclosed |
| EP-2687548-B1 | ORGANIC/INORGANIC COMPOSITE, MANUFACTURING METHOD THEREFOR, ORGANIC/INORGANIC COMPOSITE FILM, MANUFACTURING METHOD THEREFOR, PHOTONIC CRYSTAL, COATING MATERIAL, THERMOPLASTIC COMPOSITION, MICROSTRUCTURE, OPTICAL MATERIAL, ANTIREFLECTION MEMBER, AND OPTICAL LENS | ASAHI CHEMICAL IND (JP) | 2019-07-31 | — | — | EP | disclosed |
| EP-3378867-A1 | POLYHEDRAL POLYSILOXANE MODIFIED PRODUCT AND COMPOSITION USING THE MODIFIED PRODUCT | Kaneka Corporation (JP) | 2018-09-26 | — | — | EP | disclosed |
| EP-3042909-B1 | POLYHEDRAL POLYSILOXANE MODIFIED PRODUCT AND COMPOSITION USING THE MODIFIED PRODUCT | KANEKA CORP (JP) | 2018-08-01 | — | — | EP | disclosed |
| US-9464172-B2 | Alkali-developable curable composition, insulating thin film using the same, and thin film transistor | KANEKA CORPORATION (JP) | 2016-10-11 | — | — | US | disclosed |
| US-9422405-B2 | Polyhedral polysiloxane modified product and composition using the modified product | KANEKA CORPORATION (JP) | 2016-08-23 | — | — | US | disclosed |
| US-20130337161-A1 | Coating Material Containing Organic/Inorganic Composite, Organic/Inorganic Composite Film and Antireflection Member | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2013-12-19 | — | — | US | disclosed |
| US-20130165611-A1 | POLYHEDRAL POLYSILOXANE MODIFIED PRODUCT AND COMPOSITION USING THE MODIFIED PRODUCT | KANEKA CORPORATION (JP) | 2013-06-27 | — | — | US | disclosed |
| US-8399592-B2 | Polyhedral polysiloxane modified product and composition using the modified product | KANEKA CORPORATION (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20110001190-A1 | ALKALI-DEVELOPABLE CURABLE COMPOSITION, INSULATING THIN FILM USING THE SAME, AND THIN FILM TRANSISTOR | KANEKA CORPORATION (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2236543-A1 | ALKALI-DEVELOPABLE CURABLE COMPOSITION, INSULATING THIN FILM USING THE SAME, AND THIN FILM TRANSISTOR | Kaneka Corporation (JP) | 2010-10-06 | — | — | EP | disclosed |
| US-20100099790-A1 | POLYHEDRAL POLYSILOXANE MODIFIED PRODUCT AND COMPOSITION USING THE MODIFIED PRODUCT | KANEKA CORPORATION (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20100063221-A1 | POLYSILOXANE COMPOSITION | KANEKA CORPORATION | 2010-03-11 | — | — | US | disclosed |
| EP-2151443-A1 | POLYHEDRAL POLYSILOXANE MODIFIED PRODUCT AND COMPOSITION USING THE MODIFIED PRODUCT | Kaneka Corporation (JP) | 2010-02-10 | — | — | EP | disclosed |
| US-20090234072-A1 | CURABLE COMPOSITION | KANEKA CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1923431-A1 | CURABLE COMPOSITION | Kaneka Corporation (JP) | 2008-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110001190-A1 | ALKALI-DEVELOPABLE CURABLE COMPOSITION, INSULATING THIN FILM USING THE SAME, AND THIN FILM TRANSISTOR | TET1, KDM4A, ASIC1 | ALDH1A1 638/4885LMNA 3600/4885HPGD 3695/4885 |
| US-20130165611-A1 | POLYHEDRAL POLYSILOXANE MODIFIED PRODUCT AND COMPOSITION USING THE MODIFIED PRODUCT | SMCHD1, CNOT9, SMC4 | ALDH1A1 2655/4885LMNA 364/4885HPGD 4008/4885 |
| US-20100099790-A1 | POLYHEDRAL POLYSILOXANE MODIFIED PRODUCT AND COMPOSITION USING THE MODIFIED PRODUCT | SMCHD1, CNOT9, SMC4 | ALDH1A1 2655/4885LMNA 364/4885HPGD 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.