SCHEMBL105844

SCHEMBL105844

CC(C)SC1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.31
SHBG P04278 1/20 0.31
ADH1B P00325 1/20 0.30
ADH1C P00326 1/20 0.30
ADH1A P07327 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15270726 1.00 SLC2A1 (0.31) SLC2A1SHBGADH1BADH1CADH1A
SCHEMBL13081808 0.97
SCHEMBL4017588 0.91
SCHEMBL15271048 0.84
SCHEMBL7471909 0.78 ADH1B (0.32) ADH1BADH1CADH1A
SCHEMBL7482713 0.78
SCHEMBL8699020 0.78
SCHEMBL7479908 0.76 SLC2A1 (0.32) SLC2A1
SCHEMBL22764106 0.76
SCHEMBL8700759 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4059699-A O,O-diethyl-O-carboxamidophosphate esters and use to combat insects and mites GULF OIL CORPORATION (US) 1977-11-22 US claimed
US-3994997-A MITICIDES, INSECTICIDES GULF OIL CORPORATION (US) 1976-11-30 US claimed
US-20230276701-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMISSION DEVICE OSAKA UNIVERSITY (JP) 2023-08-31 US disclosed
US-20230276701-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMISSION DEVICE OSAKA UNIVERSITY (JP) 2023-08-31 US disclosed
US-11358985-B2 Tripeptide compound, preparation method therefor, and application thereof NORTHWEST UNIVERSITY (CN) 2022-06-14 US disclosed
US-20210292285-A1 HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS NUVATION BIO INC (US) 2021-09-23 US disclosed
US-11028058-B2 Heterocyclic compounds as adenosine antagonists NUVATION BIO INC. (US) 2021-06-08 US disclosed
US-10442798-B2 Tetrahydroquinoline sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease LYCERA CORPORATION (US) 2019-10-15 US disclosed
US-20190023666-A1 HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS SAGARD HOLDINGS MANAGER LP, AS ADMINISTRATIVE AGENT (CA) 2019-01-24 US disclosed
US-20180222856-A1 SELECTIVE INHIBITORS OF CARBONIC ANHYDRASE VILNIUS UNIVERSITY (LT) 2018-08-09 US disclosed
US-20180208587-A1 TETRAHYDROQUINOLINE SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORy AND THE TREATMENT OF DISEASE LYCERA CORPORATION 2018-07-26 US disclosed
US-20120059162-A1 FUSED IMIDAZOLE DERIVATIVE HAVING TTK INHIBITORY ACTION ONCOTHERAPY SCIENCE, INC. (JP) 2012-03-08 US disclosed
US-20110281874-A1 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS ARRAY BIOPHARMA INC. (US) 2011-11-17 US disclosed
US-8022223-B2 2-aminopyridine analogs as glucokinase activators ARRAY BIOPHARMA, INC. (US) 2011-09-20 US disclosed
US-20110034463-A1 TYPE III SECRETION INHIBITORS, ANALOGS AND USES THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-02-10 US disclosed
US-20090156603-A1 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS ARRAY BIOPHARMA INC. (US) 2009-06-18 US disclosed
US-4059699-A O,O-diethyl-O-carboxamidophosphate esters and use to combat insects and mites GULF OIL CORPORATION (US) 1977-11-22 US disclosed
US-4059699-A O,O-diethyl-O-carboxamidophosphate esters and use to combat insects and mites GULF OIL CORPORATION (US) 1977-11-22 US disclosed
US-3994997-A MITICIDES, INSECTICIDES GULF OIL CORPORATION (US) 1976-11-30 US disclosed
US-3994997-A MITICIDES, INSECTICIDES GULF OIL CORPORATION (US) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120059162-A1 FUSED IMIDAZOLE DERIVATIVE HAVING TTK INHIBITORY ACTION NR0B1, GRK7, NR5A2 SLC2A1 3296/4885SHBG 1931/4885ADH1B 2478/4885
US-11358985-B2 Tripeptide compound, preparation method therefor, and application thereof VIP, PREP, ACE SLC2A1 2635/4885SHBG 1918/4885ADH1B 1760/4885
US-20190023666-A1 HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS ADORA2A, ADORA3, ADORA1 SLC2A1 2020/4885SHBG 3759/4885ADH1B 2589/4885
US-20180222856-A1 SELECTIVE INHIBITORS OF CARBONIC ANHYDRASE CA9, CA2, CA7 SLC2A1 412/4885SHBG 2650/4885ADH1B 211/4885
US-20110034463-A1 TYPE III SECRETION INHIBITORS, ANALOGS AND USES THEREOF GBA3, CLPP, PEX3 SLC2A1 3863/4885SHBG 4181/4885ADH1B 4825/4885
US-11028058-B2 Heterocyclic compounds as adenosine antagonists ADORA2A, ADORA3, ADORA1 SLC2A1 2020/4885SHBG 3759/4885ADH1B 2589/4885
US-20230276701-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMISSION DEVICE ESR1, ECE1, ESYT1 SLC2A1 4326/4885SHBG 2786/4885ADH1B 2998/4885
US-20210292285-A1 HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS ADORA2A, ADORA3, ADORA1 SLC2A1 2020/4885SHBG 3759/4885ADH1B 2589/4885
US-20090156603-A1 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS GCK, GCKR, PRKCSH SLC2A1 33/4885SHBG 1539/4885ADH1B 572/4885
US-10442798-B2 Tetrahydroquinoline sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease RORA, RORC, RORB SLC2A1 3758/4885SHBG 497/4885ADH1B 871/4885
US-20180208587-A1 TETRAHYDROQUINOLINE SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORy AND THE TREATMENT OF DISEASE RORA, RORB, RORC SLC2A1 3981/4885SHBG 560/4885ADH1B 844/4885
US-20110281874-A1 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS GCK, GCKR, GALK1 SLC2A1 18/4885SHBG 3340/4885ADH1B 661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.