SCHEMBL1066809

SCHEMBL1066809

CC(=O)c1cccc(B(O)O)c1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
BCHE P06276 1/20 0.41
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPK1 P28482 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HPGD P15428 1/20 0.36
PDK2 Q15119 1/20 0.35
MAOB P27338 2/20 0.35
MAOA P21397 1/20 0.35
THRB P10828 1/20 0.34
ALB P02768 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1932772 0.84 ALB (0.47) CES2CES1BCHESMN1; SMN2ALDH1A1
SCHEMBL29956608 0.82 PARP1 (0.41) CES2CES1BCHEALDH1A1HPGD
SCHEMBL11303521 0.82 CES2 (0.39) CES2CES1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL29954759 0.79 TSHR (0.47) KMT2AALDH1A1HPGDCA12CA1
SCHEMBL31419627 0.79 MEN1 (0.43) CES2CES1BCHEKMT2ASMN1; SMN2
SCHEMBL20530659 0.79 TSHR (0.47) KMT2AALDH1A1HPGDCA12CA1
SCHEMBL29957894 0.79 MEN1 (0.43) CES2CES1BCHEKMT2ASMN1; SMN2
SCHEMBL519802 0.79 ENPP2 (0.41) KMT2ASMN1; SMN2ALDH1A1PDK2CA12
SCHEMBL29469063 0.79 ENPP2 (0.41) KMT2ASMN1; SMN2ALDH1A1PDK2CA12
SCHEMBL25745449 0.78 ENPP2 (0.42) CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112062792-A Production method of tris (dimethylamine) cyclopentadiene hafnium 芯越芯(南京)电子科技有限公司 2020-12-11 CN claimed
CN-108148089-B Preparation method of tetra (dimethylamino) titanium 浙江博瑞电子科技有限公司 2020-09-08 CN claimed
US-20260135164-A1 LITHIUM SECONDARY BATTERIES CAPABLE OF SELF-POISONING PROLOGIUM TECHNOLOGY CO., LTD. (TW) 2026-05-14 US disclosed
EP-4668366-A1 LITHIUM SECONDARY BATTERY CAPABLE OF SELF-POISONING Prologium Technology Co., Ltd. (TW) 2025-12-24 EP disclosed
CN-119998964-A Self-poisoning lithium secondary battery 辉能科技股份有限公司 2025-05-13 CN disclosed
WO-2024169769-A1 LITHIUM SECONDARY BATTERY CAPABLE OF SELF-POISONING 辉能科技股份有限公司 2024-08-22 WO disclosed
CN-112062792-A Production method of tris (dimethylamine) cyclopentadiene hafnium 芯越芯(南京)电子科技有限公司 2020-12-11 CN disclosed
CN-108148089-B Preparation method of tetra (dimethylamino) titanium 浙江博瑞电子科技有限公司 2020-09-08 CN disclosed
US-20190218215-A1 CYANO-SUBTITUTED HETEROCYCLES WITH ACTIVITY AS INHIBITORS OF USP30 MISSION THERAPEUTICS LIMITED (GB) 2019-07-18 US disclosed
EP-2858990-B1 PYRIDINONE AND PYRIDAZINONE DERIVATIVES ABBVIE INC (US) 2018-05-16 EP disclosed
US-9561231-B2 Pyridinone and pyridazinone derivatives ABBVIE INC. (US) 2017-02-07 US disclosed
EP-2274297-A1 PYRROLIDINONE GLUCOKINASE ACTIVATORS F. Hoffmann-La Roche AG (CH) 2011-01-19 EP disclosed
EP-2264017-A1 HETEROCYCLIC DERIVATIVE AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2010-12-22 EP disclosed
US-7741327-B2 Pyrrolidinone glucokinase activators HOFFMANN-LA ROCHE INC. (US) 2010-06-22 US disclosed
US-20090275591-A1 1-HETEROCYCLYLSULFONYL, 2-AMINOMETHYL, 5- (HETERO-) ARYL SUBSTITUTED 1-H-PYRROLE DERIVATIVES AS ACID SECRETION INHIBITOR TAKEDA PHARMACEUTICAL COMPANY LIMTED (JP) 2009-11-05 US disclosed
US-20090264445-A1 PYRROLIDINONE GLUCOKINASE ACTIVATORS BERTHEL STEVEN JOSEPH 2009-10-22 US disclosed
WO-2009127546-A1 PYRROLIDINONE GLUCOKINASE ACTIVATORS F. HOFFMANN-LA ROCHE AG (CH) 2009-10-22 WO disclosed
US-20090143444-A1 ACID SECRETION INHIBITOR TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-06-04 US disclosed
US-7498337-B2 Acid secretion inhibitor TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-03-03 US disclosed
US-20070060623-A1 antiulcer agents; proton pump inhibitors; side effect reduction; 1-[4-fluoro-5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine; superior acid secretion inhibitory effect; peptic ulcer, Zollinger-Ellison syndrome, reflux esophagitis, or symptomatic gastroesophageal reflux disease TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260135164-A1 LITHIUM SECONDARY BATTERIES CAPABLE OF SELF-POISONING L3MBTL3, HAO2, LDHB CES2 3117/4885CES1 4462/4885BCHE 177/4885
US-20090143444-A1 ACID SECRETION INHIBITOR HRH2, VIP, CCKBR CES2 1439/4885CES1 104/4885BCHE 387/4885
US-20190218215-A1 CYANO-SUBTITUTED HETEROCYCLES WITH ACTIVITY AS INHIBITORS OF USP30 USP30, USP28, USP1 CES2 1049/4885CES1 547/4885BCHE 1743/4885
US-20090264445-A1 PYRROLIDINONE GLUCOKINASE ACTIVATORS GCKR, GCK, PDK2 CES2 2323/4885CES1 1069/4885BCHE 2642/4885
US-20090275591-A1 1-HETEROCYCLYLSULFONYL, 2-AMINOMETHYL, 5- (HETERO-) ARYL SUBSTITUTED 1-H-PYRROLE DERIVATIVES AS ACID SECRETION INHIBITOR HRH2, ASNS, GHSR CES2 1276/4885CES1 73/4885BCHE 423/4885
US-20070060623-A1 antiulcer agents; proton pump inhibitors; side effect reduction; 1-[4-fluoro-5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine; superior acid secretion inhibitory effect; peptic ulcer, Zollinger-Ellison syndrome, reflux esophagitis, or symptomatic gastroesophageal reflux disease HRH2, GIPR, HRH4 CES2 3007/4885CES1 355/4885BCHE 2538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.