SCHEMBL1068915

SCHEMBL1068915

Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(O)N(C=O)C2CC2)[C@@H](O)[C@H]1O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ AHCY P23526 8/20 0.60
▸ TMEM97 Q5BJF2 2/20 0.56
▸ HIF1A Q16665 1/20 0.56
▸ SIGMAR1 Q99720 1/20 0.56
▸ ADORA2A P29274 4/20 0.55
▸ ADORA2B P29275 4/20 0.55
▸ HSP90B1 P14625 3/20 0.55
▸ ADORA3 P0DMS8 3/20 0.55
▸ ADORA1 P30542 3/20 0.55
▸ RXFP1 Q9HBX9 1/20 0.55
▸ HRH1 P35367 1/20 0.55
▸ CYP3A4 P08684 1/20 0.55
▸ TSHR P16473 1/20 0.55
▸ MAPK1 P28482 1/20 0.55
▸ BLM P54132 1/20 0.55
▸ PRMT5 O14744 1/20 0.54
▸ WDR77 Q9BQA1 1/20 0.54
▸ HSP90AA1 P07900 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1972796 0.85 AHCY (0.63) AHCYTMEM97HIF1ASIGMAR1ADORA2A
SCHEMBL6695446 0.85 AHCY (0.53) AHCYTMEM97HIF1ASIGMAR1ADORA2A
SCHEMBL29877256 0.83 AHCY (0.61) AHCYTMEM97HIF1ASIGMAR1ADORA2A
SCHEMBL28901883 0.83 AHCY (0.61) AHCYTMEM97HIF1ASIGMAR1ADORA2A
SCHEMBL177772 0.83 AHCY (0.61) AHCYTMEM97HIF1ASIGMAR1ADORA2A
SCHEMBL8661748 0.81 AHCY (0.69) AHCYTMEM97HIF1ASIGMAR1ADORA2A
SCHEMBL8661561 0.81 AHCY (0.69) AHCYTMEM97HIF1ASIGMAR1ADORA2A
SCHEMBL31680251 0.81 AHCY (0.68) AHCYTMEM97HIF1ASIGMAR1ADORA2A
SCHEMBL397800 0.81 AHCY (0.68) AHCYTMEM97HIF1ASIGMAR1ADORA2A
SCHEMBL7803295 0.80 AHCY (0.67) AHCYTMEM97HIF1ASIGMAR1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2204154-B1 Association of monosaccharides and adenosine and its cosmetic use ORÉAL L (FR) 2016-10-12 — — EP claimed
US-20100168049-A1 COMBINATION OF MONOSACCHARIDES AND ADENOSINE AND USE THEREOF L'OREAL (FR) 2010-07-01 — — US claimed
US-20070232560-A1 Treatment of skin with adenosine or adenosine analog UNIVERSITY OF MASSACHUSETTS, A MASSACHUSETTS CORPORATION 2007-10-04 — — US claimed
EP-1424064-B1 Use of adenosin or an adenosin analog to smooth out fine lines OREAL (FR) 2007-06-06 — — EP claimed
US-20060240056-A1 Treatment of skin with adenosine or adenosine analog UNIVERSITY OF MASSACHUSETTS, A MASSACHUSETTS CORPORATION 2006-10-26 — — US claimed
US-20040146474-A1 Method for softening lines and relaxing the skin with adenosine and adenosine analogues L'OREAL (FR) 2004-07-29 — — US claimed
US-6020321-A Adenosine receptor agonists for the promotion of wound healing NEW YORK UNIVERSITY (US) 2000-02-01 — — US claimed
US-5932558-A PROMOTE MIGRATION OF ENDOTHELIAL CELLS, FIBROBLASTS AND EPITHELIAL CELLS NEW YORK UNIVERSITY (US) 1999-08-03 — — US claimed
US-5424297-A Adenosine dextran conjugates UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) 1995-06-13 — — US claimed
US-20260137604-A1 COSMETIC COMPOSITIONS L'OREAL (FR) 2026-05-21 — — US disclosed
US-20260069521-A1 COSMETIC COMPOSITION FOR IMPROVED PENETRATION L'OREAL (FR) 2026-03-12 — — US disclosed
EP-4440531-B1 KIT AND METHOD FOR TREATING SKIN OREAL (FR) 2026-01-21 — — EP disclosed
US-12508217-B2 Cosmetic compositions comprising high amounts of hydroxypropyl tetrahydropyrantriol L'OREAL (FR) 2025-12-30 — — US disclosed
US-12491146-B1 Skin brightening compositions with thiopyridinone compound L'OREAL (FR) 2025-12-09 — — US disclosed
WO-1998022137-A1 SUPPRESSION OF TNF α AND IL-12 IN THERAPY THE KENNEDY INSTITUTE OF RHEUMATOLOGY (GB) 1998-05-28 — — WO disclosed
WO-1998005357-A1 ANTI-TNF ANTIBODIES AND METHOTREXATE IN THE TREATMENT OF AUTOIMMUNE DISEASE THE KENNEDY INSTITUTE OF RHEUMATOLOGY (GB) 1998-02-12 — — WO disclosed
WO-1997030088-A2 METHODS OF TREATING VASCULAR DISEASE WITH TNF ANTAGONISTS THE KENNEDY INSTITUTE OF RHEUMATOLOGY (GB) 1997-08-21 — — WO disclosed
EP-0755255-A1 TREATMENT OF TOXOPLASMOSIS UNIVERSITY OF ALABAMA, BIRMINGHAM RESEARCH FOUNDATION (US) 1997-01-29 — — EP disclosed
WO-1996018398-A1 TREATMENT OF TOXOPLASMOSIS THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION (US) 1996-06-20 — — WO disclosed
US-5424297-A Adenosine dextran conjugates UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) 1995-06-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137604-A1 COSMETIC COMPOSITIONS TYR, CUTA, LAGE3 AHCY 1793/4885TMEM97 2053/4885HIF1A 3976/4885
US-12491146-B1 Skin brightening compositions with thiopyridinone compound GLMN, GNMT, GLA AHCY 578/4885TMEM97 3071/4885HIF1A 4270/4885
US-12508217-B2 Cosmetic compositions comprising high amounts of hydroxypropyl tetrahydropyrantriol CYP24A1, CYP2R1, CCND3 AHCY 2211/4885TMEM97 1378/4885HIF1A 964/4885
US-20260069521-A1 COSMETIC COMPOSITION FOR IMPROVED PENETRATION CUTA, SLC14A1, DSG1 AHCY 196/4885TMEM97 923/4885HIF1A 2033/4885
US-20100168049-A1 COMBINATION OF MONOSACCHARIDES AND ADENOSINE AND USE THEREOF ADORA2A, ADORA1, ADORA3 AHCY 257/4885TMEM97 3704/4885HIF1A 1247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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