Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27138913 | 0.72 | RAD51 (0.72) | ALDH1A1SMN1; SMN2MAPTHPGDNPC1 | |
| SCHEMBL10789785 | 0.70 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTHPGDNPC1 | |
| SCHEMBL11681231 | 0.69 | NPC1 (0.55) | ALDH1A1SMN1; SMN2MAPTHPGDNPC1 | |
| SCHEMBL11420389 | 0.69 | CASP3 (0.59) | ALDH1A1SMN1; SMN2MAPTHPGDNPC1 | |
| SCHEMBL16149341 | 0.67 | NPC1 (0.74) | ALDH1A1SMN1; SMN2MAPTHPGDNPC1 | |
| SCHEMBL6503058 | 0.67 | TP53 (0.61) | ALDH1A1SMN1; SMN2MAPTHPGDNPC1 | |
| SCHEMBL10745615 | 0.67 | CA12 (0.55) | ALDH1A1HPGDGAA | |
| SCHEMBL4940015 | 0.66 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPTHPGDNPC1 | |
| SCHEMBL4935349 | 0.66 | NPC1 (0.74) | ALDH1A1SMN1; SMN2MAPTHPGDNPC1 | |
| SCHEMBL15333643 | 0.66 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2MAPTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0075996-B1 | DETERGENT COMPOSITIONS CONTAINING ALKYLPOLYSACCHARIDE AND NONIONIC SURFACTANT MIXTURE AND ANIONIC OPTICAL BRIGHTENER | THE PROCTER & GAMBLE COMPANY (US) | 1987-01-21 | — | — | EP | claimed |
| US-4483779-A | Detergent compositions comprising polyglycoside and polyethoxylate surfactants and anionic fluorescer | THE PROCTER & GAMBLE COMPANY (US) | 1984-11-20 | — | — | US | claimed |
| EP-0075996-B1 | DETERGENT COMPOSITIONS CONTAINING ALKYLPOLYSACCHARIDE AND NONIONIC SURFACTANT MIXTURE AND ANIONIC OPTICAL BRIGHTENER | THE PROCTER & GAMBLE COMPANY (US) | 1987-01-21 | — | — | EP | disclosed |
| US-4483779-A | Detergent compositions comprising polyglycoside and polyethoxylate surfactants and anionic fluorescer | THE PROCTER & GAMBLE COMPANY (US) | 1984-11-20 | — | — | US | disclosed |
| US-4483780-A | Detergent compositions containing polyglycoside and polyethoxylate detergent surfactants | THE PROCTER & GAMBLE COMPANY (US) | 1984-11-20 | — | — | US | disclosed |