Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31312357 | 0.96 | LMNA (0.46) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL15525107 | 0.84 | LMNA (0.46) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL5634372 | 0.84 | ERN1 (0.47) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL3437884 | 0.79 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL31532126 | 0.73 | LMNA (0.60) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL7634333 | 0.72 | LMNA (0.46) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL7630667 | 0.72 | LMNA (0.46) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL2453380 | 0.70 | TSHR (0.41) | LMNAKMT2AMEN1TDP1ALDH1A1 | |
| Ortho-Phthalaldehyde SCHEMBL28379746 | 0.69 | LMNA (0.93) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL439492 | 0.69 | ESR1 (0.48) | LMNAKMT2AMEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3231413-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2025-03-19 | — | — | EP | disclosed |
| EP-3335689-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2025-03-19 | — | — | EP | disclosed |
| US-20240180791-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2024-06-06 | — | — | US | disclosed |
| US-11931432-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DENTSPLY SIRONA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11844848-B2 | Photocurable dental composition | DENTSPLY SIRONA INC. (US) | 2023-12-19 | — | — | US | disclosed |
| EP-3246001-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2023-03-29 | — | — | EP | disclosed |
| EP-3478244-B1 | DENTAL COMPOSITION COMPRISING A DENTAL FILLER CONTAINING A STRUCTURAL FILLER AND SILANATED GLASS FLAKES | DENTSPLY DETREY GMBH (DE) | 2022-10-26 | — | — | EP | disclosed |
| US-11433004-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2022-09-06 | — | — | US | disclosed |
| EP-3360532-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2022-04-27 | — | — | EP | disclosed |
| WO-2017198843-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-11-23 | — | — | WO | disclosed |
| WO-2017198840-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-11-23 | — | — | WO | disclosed |
| EP-3246002-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GmbH (DE) | 2017-11-22 | — | — | EP | disclosed |
| EP-3246001-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GmbH (DE) | 2017-11-22 | — | — | EP | disclosed |
| WO-2017178383-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |
| EP-3231413-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GmbH (DE) | 2017-10-18 | — | — | EP | disclosed |
| WO-2017060527-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-04-13 | — | — | WO | disclosed |
| WO-2017060459-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-04-13 | — | — | WO | disclosed |
| EP-3153150-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2017-04-12 | — | — | EP | disclosed |
| US-4588715-A | ASNTICHOLESTEROL AGENTS, ATHEROSCLEROSIS, SILYLPHENYL DERIVATIVES | SANDOZ, INC. (US) | 1986-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240180791-A1 | DENTAL COMPOSITION | CAD, MTR, ESD | LMNA 4196/4885KMT2A 1917/4885MEN1 3344/4885 |
| US-11433004-B2 | Dental composition | F12, F11, F9 | LMNA 570/4885KMT2A 2420/4885MEN1 3657/4885 |
| US-11931432-B2 | Dental composition | CAD, MTR, ESD | LMNA 4196/4885KMT2A 1917/4885MEN1 3344/4885 |
| US-11844848-B2 | Photocurable dental composition | TST, SULT1A1, SULT2A1 | LMNA 3664/4885KMT2A 834/4885MEN1 4629/4885 |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DHX35, DHX30, FLNA | LMNA 469/4885KMT2A 3471/4885MEN1 3347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.