Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828058 | 0.76 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1 | |
| Potassium Ion SCHEMBL4148709 | 0.72 | TP53 (0.35) | L3MBTL1 | |
| SCHEMBL3023228 | 0.68 | HSP90AA1 (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL829566 | 0.64 | MAPT (0.33) | L3MBTL1 | |
| SCHEMBL16944044 | 0.64 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1 | |
| SCHEMBL6121968 | 0.63 | GSK3B (0.35) | ALDH1A1L3MBTL1 | |
| SCHEMBL2616850 | 0.61 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1 | |
| Bromide SCHEMBL6115300 | 0.61 | GSK3B (0.34) | ALDH1A1L3MBTL1 | |
| SCHEMBL2776999 | 0.61 | — | — | |
| SCHEMBL8349405 | 0.60 | IGF1R (0.38) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469622-A | Method for preventing rusting in silver by using novel imidazole-4(5)-dithiocarboxylic acids in organic solvent | SHIKOKU CHEMICALS CORPORATION (JP) | 1984-09-04 | — | — | US | disclosed |
| US-4394511-A | Imidazole 4(5)-dithiocarboxylic acids or salts | SHIKOKU CHEMICALS CORPORATION (JP) | 1983-07-19 | — | — | US | disclosed |