SCHEMBL1126440

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126827	0.93	ALDH1A1 (0.46)	ALDH1A1PKMMAPK1HPGDTDP1
	SCHEMBL1126720	0.86	TNF (0.44)	ALDH1A1MAPK1HPGDCNR2DGAT2
	SCHEMBL1127201	0.83	MEN1 (0.44)	ALDH1A1PKMMAPK1L3MBTL1SMN1; SMN2
	SCHEMBL1127303	0.75	CHRNB2 (0.50)	ALDH1A1HPGDCNR2CYP2C9SMN1; SMN2
	SCHEMBL1127378	0.74	HPGD (0.41)	ALDH1A1MAPK1HPGDTDP1CNR2
	SCHEMBL1127123	0.73	ALDH1A1 (0.40)	ALDH1A1HPGDTDP1CNR2SMN1; SMN2
	SCHEMBL1127213	0.72	NPC1 (0.39)	ALDH1A1HPGDCYP2C9SMN1; SMN2
	SCHEMBL1989043	0.71	MAPT (0.38)	POLB
	SCHEMBL1989483	0.71	KCNH2 (0.41)	ALDH1A1MAPK1SMN1; SMN2LMNAPOLB
	SCHEMBL1126522	0.71	MAPT (0.37)	LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.