SCHEMBL1126720

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127303	0.88	CHRNB2 (0.50)	CYP2C9NTRK1NTRK3CHRNB2CHRNB4
	SCHEMBL1126440	0.86	ALDH1A1 (0.46)	TNFCYP2C9NPY5RCHRNB2CHRNB4
	SCHEMBL1126896	0.81	RAB9A (0.49)	SMN1; SMN2ALDH1A1KMT2AMAPTMEN1
	SCHEMBL1127233	0.80	MEN1 (0.50)	NPY5RSMN1; SMN2ALDH1A1KMT2AMAPT
	SCHEMBL1126812	0.79	ALDH1A1 (0.48)	SMN1; SMN2ALDH1A1KMT2AMEN1MAPK1
	SCHEMBL1126783	0.79	RAB9A (0.42)	CHRNB2CHRNB4CHRNA3CHRNA4SMN1; SMN2
	SCHEMBL1126827	0.79	ALDH1A1 (0.46)	TRPV1NPY5RSMN1; SMN2ALDH1A1KMT2A
	SCHEMBL1989265	0.74	MAPK1 (0.46)	SMN1; SMN2ALDH1A1KMT2AMEN1MAPK1
	SCHEMBL1127545	0.74	RAB9A (0.50)	TRPV1SMN1; SMN2ALDH1A1MAPTLMNA
	SCHEMBL1126931	0.74	RAB9A (0.46)	SMN1; SMN2ALDH1A1KMT2AMAPTCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.