SCHEMBL1127201

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127233	0.86	MEN1 (0.50)	MEN1KMT2AALDH1A1SMN1; SMN2PABPC1
	SCHEMBL1126440	0.83	ALDH1A1 (0.46)	ALDH1A1SMN1; SMN2L3MBTL1PKMMAPK1
	SCHEMBL1127213	0.75	NPC1 (0.39)	ALDH1A1SMN1; SMN2KDM4EMAPT
	SCHEMBL1127171	0.74	POLB (0.42)	MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1
	SCHEMBL1127378	0.74	HPGD (0.41)	ALDH1A1SMN1; SMN2HSD17B10MAPK1MAPT
	SCHEMBL15161945	0.74	HTR1A (0.44)	MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1
	SCHEMBL1126693	0.74	MEN1 (0.49)	MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1
	SCHEMBL1127123	0.73	ALDH1A1 (0.40)	MEN1KMT2AALDH1A1SMN1; SMN2MAPT
	SCHEMBL1989043	0.72	MAPT (0.38)	KDM4EMAPTPOLB
	SCHEMBL1127303	0.71	CHRNB2 (0.50)	MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.