SCHEMBL11297204

SCHEMBL11297204

CC(C)c1cccc(S(=O)(=O)[O-])c1C(C)C.[Na+]

nearest known ligand 0.38

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 2/20 0.38
CA2 known ✓ P00918 2/20 0.38
GABRA1 known ✓ P14867 2/20 0.38
GABRG2 known ✓ P18507 2/20 0.38
GABRB3 known ✓ P28472 2/20 0.38
GABRB1 known ✓ P18505 1/20 0.38
PTGS1 known ✓ P23219 1/20 0.38
GABRA5 known ✓ P31644 1/20 0.38
GABRA3 known ✓ P34903 1/20 0.38
GABRA2 known ✓ P47869 1/20 0.38
GABRB2 known ✓ P47870 1/20 0.38
GABRA4 known ✓ P48169 1/20 0.38
GABRA6 known ✓ Q16445 1/20 0.38
CA12 known ✓ O43570 1/20 0.37
FAAH O00519 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL11311144 0.96 GABRA1 (0.39) CA1CA2GABRA1GABRG2GABRB3
Potassium Ion SCHEMBL7026962 0.96 CA1 (0.38) CA1CA2GABRA1GABRG2GABRB3
SCHEMBL9164110 0.83 SLC9A1 (0.33) CA1CA2LMNAHPGDL3MBTL1
SCHEMBL27656927 0.82 CA1 (0.44) CA1CA2CA9
SCHEMBL67965 0.82 HSD11B1 (0.46) CA1CA2GABRA1GABRG2GABRB3
SCHEMBL29615335 0.82 HSD11B1 (0.46) CA1CA2GABRA1GABRG2GABRB3
SCHEMBL9109689 0.82 HSD11B1 (0.46) CA1CA2GABRA1GABRG2GABRB3
SCHEMBL30130401 0.82 HSD11B1 (0.46) CA1CA2GABRA1GABRG2GABRB3
Hydrogen Peroxide SCHEMBL11316859 0.82 CYP1A2 (0.39) CA1CA2GABRA1GABRG2GABRB3
SCHEMBL7786711 0.82 NR4A1 (0.34) CA1CA2GABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0005098-B1 COMPOSITIONS CONTAINING ALKALI METAL MONO- OR POLYALKYLARYLSULFONATE AND THE CORRESPONDING HYDROPEROXIDE; PROCESS FOR THEIR PREPARATION AND DETERGENT COMPOSITIONS CONTAINING THEM Société Chimique des Charbonnages (FR) 1982-02-03 EP claimed
CN-117624033-A Ligand compound, iron/nickel complex, catalyst, preparation method and application thereof 中国科学技术大学 2024-03-01 CN disclosed
EP-3864963-A1 OILY SUSPENSION AGROCHEMICAL COMPOSITION Kumiai Chemical Industry Co., Ltd. (JP) 2021-08-18 EP disclosed
CN-1200737-C Sterilising agents and method ALLIED BIO CO LTD (GB) 2005-05-11 CN disclosed
CN-1473192-A Detergent composition 2004-02-04 CN disclosed
CN-1426453-A Package for unit dose detergent and method of use thereof PROCTER & GAMBLE (US) 2003-06-25 CN disclosed
CN-1391488-A Sterilising agents and method ALLIED BIO CORP LTD (GB) 2003-01-15 CN disclosed
US-4294717-A BLEACHES, HYDROPEROXIDATION SOCIETE CHIMIQUE DES CHARBONNAGES SA (FR) 1981-10-13 US disclosed