Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380547 | 0.88 | MGLL (0.48) | PDE4APDE4BPDE4CPDE4DCA12 | |
| SCHEMBL11374823 | 0.86 | L3MBTL1 (0.49) | PDE4APDE4BPDE4CPDE4DCHEK2 | |
| SCHEMBL11381968 | 0.80 | WDR5 (0.41) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL11377089 | 0.79 | MEN1 (0.46) | MGLLMAPTTDP1TP53POLB | |
| SCHEMBL11383158 | 0.77 | CBFB (0.52) | PDE4APDE4BPDE4CPDE4DCA12 | |
| SCHEMBL11377673 | 0.77 | ALDH1A1 (0.57) | MGLLLMNAMAPTPOLBMAPK1 | |
| SCHEMBL11375670 | 0.76 | GUSB (0.56) | CHEK2LMNAMAPTTDP1TP53 | |
| SCHEMBL11390124 | 0.76 | PDE5A (0.41) | MGLLMAPTTDP1TP53POLB | |
| SCHEMBL11375402 | 0.76 | AMY1A (0.50) | LMNAMAPTTDP1TP53POLB | |
| SCHEMBL11383000 | 0.75 | PDE5A (0.44) | PDE4APDE4BPDE4CPDE4DCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |