Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28478970 | 1.00 | DNM1 (0.42) | DNM1PSMD14PLA2G1BMMP2RAD52 | |
| Hydrochloric Acid SCHEMBL29078674 | 1.00 | DNM1 (0.42) | DNM1PSMD14PLA2G1BMMP2RAD52 | |
| Hydrochloric Acid SCHEMBL30211833 | 1.00 | DNM1 (0.42) | DNM1PSMD14PLA2G1BMMP2RAD52 | |
| Hydrochloric Acid SCHEMBL28336675 | 1.00 | DNM1 (0.42) | DNM1PSMD14PLA2G1BMMP2RAD52 | |
| Hydrochloric Acid SCHEMBL1701782 | 1.00 | DNM1 (0.42) | DNM1PSMD14PLA2G1BMMP2RAD52 | |
| Hydrochloric Acid SCHEMBL4607824 | 1.00 | DNM1 (0.42) | DNM1PSMD14PLA2G1BMMP2RAD52 | |
| Hydrochloric Acid SCHEMBL28467736 | 1.00 | DNM1 (0.42) | DNM1PSMD14PLA2G1BMMP2RAD52 | |
| Hydrochloric Acid SCHEMBL9465437 | 1.00 | DNM1 (0.42) | DNM1PSMD14PLA2G1BMMP2RAD52 | |
| Hydrochloric Acid SCHEMBL21253135 | 1.00 | DNM1 (0.42) | DNM1PSMD14PLA2G1BMMP2RAD52 | |
| Hydrochloric Acid SCHEMBL117037 | 1.00 | DNM1 (0.42) | DNM1PSMD14PLA2G1BMMP2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358335-B1 | BLEACHING/HIGHLIGHTING COMPOSITION | KAO GERMANY GMBH (DE) | 2013-10-16 | — | — | EP | claimed |
| US-20120024309-A1 | Bleaching/Highlighting Composition | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2012-02-02 | — | — | US | claimed |
| EP-2358335-A1 | BLEACHING/HIGHLIGHTING COMPOSITION | KPSS-Kao Professional Salon Services GmbH (DE) | 2011-08-24 | — | — | EP | claimed |
| WO-2010060601-A1 | BLEACHING/HIGHLIGHTING COMPOSITION | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-06-03 | — | — | WO | claimed |
| EP-2191812-A1 | Bleaching/Highlighting composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-06-02 | — | — | EP | claimed |
| US-12605325-B2 | Hair styling compositions for improving the elongation of hair curls | L'OREAL (FR) | 2026-04-21 | — | — | US | disclosed |
| US-12599546-B2 | Hair treatment compositions, kits thereof, and methods thereof | L'OREAL (FR) | 2026-04-14 | — | — | US | disclosed |
| US-12589065-B2 | Hair care system, hair care method and use of a hair care system | L'OREAL (FR) | 2026-03-31 | — | — | US | disclosed |
| US-12551422-B2 | Compositions and methods for styling the hair | L'ORÉAL (FR) | 2026-02-17 | — | — | US | disclosed |
| EP-4633589-A1 | HAIR TREATMENT COMPOSITIONS THAT IMPART SHINE AND LUSTER | L'OREAL (FR) | 2025-10-22 | — | — | EP | disclosed |
| US-12383483-B2 | Compositions and methods for styling the hair | L'OREAL (FR) | 2025-08-12 | — | — | US | disclosed |
| US-12290589-B2 | Cosmetic and personal care compositions containing cationic surfactants and anionic compounds | L'OREAL (FR) | 2025-05-06 | — | — | US | disclosed |
| EP-2191812-A1 | Bleaching/Highlighting composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-06-02 | — | — | EP | disclosed |
| EP-2191863-A1 | Composition for the permanent shaping of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-06-02 | — | — | EP | disclosed |
| WO-2010046077-A2 | COLOURING COMPOSITION | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046080-A2 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-04-29 | — | — | WO | disclosed |
| EP-2177204-A1 | Colouring composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-04-21 | — | — | EP | disclosed |
| EP-2177205-A1 | Composition for the permanent shaping of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-04-21 | — | — | EP | disclosed |
| WO-2010025894-A2 | CONDITIONING COMPOSITION FOR HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |
| EP-2161016-A1 | Conditioning composition for hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12605325-B2 | Hair styling compositions for improving the elongation of hair curls | SGMS1, SGMS2, SGPL1 | DNM1 1754/4885PSMD14 1776/4885PLA2G1B 408/4885 |
| US-12551422-B2 | Compositions and methods for styling the hair | DPM1, PIK3C3, SMURF1 | DNM1 3148/4885PSMD14 3255/4885PLA2G1B 458/4885 |
| US-20120024309-A1 | Bleaching/Highlighting Composition | KRT18, CRYAB, CRYAA | DNM1 1961/4885PSMD14 1951/4885PLA2G1B 1270/4885 |
| US-12589065-B2 | Hair care system, hair care method and use of a hair care system | ASH2L, ALG3, PLOD3 | DNM1 2868/4885PSMD14 2187/4885PLA2G1B 2848/4885 |
| US-12599546-B2 | Hair treatment compositions, kits thereof, and methods thereof | EBP, FHIT, BRDT | DNM1 2400/4885PSMD14 2819/4885PLA2G1B 3583/4885 |
| US-12290589-B2 | Cosmetic and personal care compositions containing cationic surfactants and anionic compounds | CUTA, SGMS1, PHOSPHO1 | DNM1 2110/4885PSMD14 4420/4885PLA2G1B 375/4885 |
| US-12383483-B2 | Compositions and methods for styling the hair | SGMS1, SGMS2, DPM1 | DNM1 3457/4885PSMD14 3384/4885PLA2G1B 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.