Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | GSK3B | P49841 | 2/20 | 0.67 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL11817466 | 0.96 | MAPK1 (0.61) | MAPK1ALDH1A1GSK3BTRPA1HIF1A | |
| SCHEMBL9218253 | 0.87 | SMN1; SMN2 (0.69) | MAPK1ALDH1A1GSK3BTRPA1HIF1A | |
| SCHEMBL318784 | 0.86 | TDP1 (0.72) | MAPK1ALDH1A1GSK3BTRPA1HIF1A | |
| SCHEMBL719034 | 0.85 | NR4A2 (0.85) | MAPK1ALDH1A1GSK3BTRPA1HIF1A | |
| SCHEMBL30121738 | 0.85 | NR4A2 (0.85) | MAPK1ALDH1A1GSK3BTRPA1HIF1A | |
| SCHEMBL2238406 | 0.85 | TDP1 (0.76) | MAPK1ALDH1A1GSK3BTRPA1HIF1A | |
| SCHEMBL29506825 | 0.85 | TDP1 (0.69) | MAPK1ALDH1A1GSK3BTRPA1HIF1A | |
| SCHEMBL11374661 | 0.84 | RAB9A (0.59) | MAPK1ALDH1A1GSK3BTRPA1HIF1A | |
| SCHEMBL633401 | 0.83 | TDP1 (0.80) | MAPK1ALDH1A1GSK3BTRPA1HIF1A | |
| Ethylene SCHEMBL10973512 | 0.83 | TDP1 (0.67) | MAPK1ALDH1A1GSK3BTRPA1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954624-A | Method for efficiently synthesizing 3-chloro-propiophenone | 山东极地医药科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-118685463-B | Dapoxetine chiral intermediates of statins enzymatic synthesis of bodies | 杭州微远生物科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119614529-A | Short-chain dehydrogenase, engineering bacteria and application thereof in asymmetric reduction of potential chiral carbonyl compounds | 杭州文德阶生物科技有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119595791-A | Detection and analysis method for mutation-causing impurities in tomoxetine hydrochloride key starting material 3-chloropropanol | 植恩生物技术股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-118771958-A | Preparation method of R- (+) -3-chloropropanol | 山东省药学科学院 | 2024-10-15 | — | — | CN | claimed |
| CN-118685463-A | Dapoxetine chiral intermediates of statins enzymatic synthesis of bodies | 杭州微远生物科技有限公司 | 2024-09-24 | — | — | CN | claimed |
| CN-117363667-B | Use of imine reductase in preparation of dapoxetine intermediate and/or dapoxetine | 欣雅利华生物技术(上海)有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117451880-A | Method for measuring dapoxetine hydrochloride impurity by using supercritical fluid chromatography | 海南卓力制药有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-117363667-A | Use of imine reductase in preparation of dapoxetine intermediate and/or dapoxetine | 欣雅利华生物技术(上海)有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-117229194-A | One-pot two-step lignin-based carbazole derivative synthesis method | 中国科学院大连化学物理研究所 | 2023-12-15 | — | — | CN | claimed |
| US-20080207956-A1 | Alkylation a corresponding alcoholic compound | DUCHESNAY INC. (CA) | 2008-08-28 | — | — | US | claimed |
| WO-2008099059-A1 | METHOD FOR THE PREPARATION OF THERAPEUTICALLY VALUABLE TRIPHENYLBUTENE DERIVATIVES | HORMOS MEDICAL LTD (FI) | 2008-08-21 | — | — | WO | claimed |
| EP-1602369-A2 | Bupropion Metabolites and Methods of their Synthesis and Use | Sepracor, Inc. (US) | 2005-12-07 | — | — | EP | claimed |
| US-20050096318-A1 | Pharmaceutically active morpholinol | GLAXOSMITHKLINE SPA (IT) | 2005-05-05 | — | — | US | claimed |
| US-6855820-B2 | Pharmaceutically active morpholinol | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-15 | — | — | US | claimed |
| EP-1259243-A2 | BUPROPION METABOLITES AND METHODS OF THEIR SYNTHESIS AND USE | SEPRACOR, INC. (US) | 2002-11-27 | — | — | EP | claimed |
| US-20020052341-A1 | Bupropion metabolites and methods of their synthesis and use | SEPRACOR INC. | 2002-05-02 | — | — | US | claimed |
| WO-2001062257-A2 | BUPROPION METABOLITES AND METHODS OF THEIR SYNTHESIS AND USE | SEPRACOR INC. (US) | 2001-08-30 | — | — | WO | claimed |
| EP-0038071-B1 | NEW UNLABELLED AND RADIOACTIVE LABELLED DERIVATIVES OF BUTYLAMINO PROPIOPHENONE, THEIR PREPARATION, IMMUNOGENS OBTAINED FROM THE UNLABELLED DERIVATIVES AND A PROCESS FOR IMMUNOGEN PREPARATION, ANTISERA RAISED USING THE IMMUNOGENS AND A METHOD FOR RAISING ANTISERA, A RADIOIMMUNOASSAY METHOD AND A TEST KIT FOR USE IN THE ASSAY METHOD | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-11-14 | — | — | EP | claimed |
| US-4025580-A | ACYLATION IN PRESENCE OF LEWIS ACID CATALYST; BIODEGRADABLE PACKAGING | OWENS-ILLINOIS, INC. (US) | 1977-05-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052341-A1 | Bupropion metabolites and methods of their synthesis and use | MAOB, MAOA, HTR5A | MAPK1 1996/4885ALDH1A1 447/4885GSK3B 476/4885 |
| US-20050096318-A1 | Pharmaceutically active morpholinol | ACHE, COMT, SNCA | MAPK1 4119/4885ALDH1A1 1559/4885GSK3B 415/4885 |
| US-20080207956-A1 | Alkylation a corresponding alcoholic compound | CYP2E1, PNMT, ADH1A | MAPK1 2129/4885ALDH1A1 21/4885GSK3B 999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.