SCHEMBL12048321

SCHEMBL12048321

CN(c1ccc(-c2ccc(N(c3ccccc3)c3ccc4ccccc4c3)cc2)cc1)c1cc2ccccc2c2ccccc12

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHKA P35790 5/20 0.36
GPR84 Q9NQS5 2/20 0.35
KDM4E B2RXH2 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
PDE5A O76074 2/20 0.33
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CHKB Q9Y259 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HIF1A Q16665 1/20 0.32
CYP1B1 Q16678 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ITK Q08881 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12048036 0.97 GPR84 (0.35) CHKAGPR84KDM4EL3MBTL1PDE5A
SCHEMBL12048548 0.97 GPR84 (0.35) CHKAGPR84KDM4EL3MBTL1PDE5A
SCHEMBL12048449 0.97 L3MBTL1 (0.35) CHKAGPR84KDM4EL3MBTL1LMNA
SCHEMBL12047816 0.96 KDM4E (0.36) CHKAKDM4EL3MBTL1PDE5ALMNA
SCHEMBL12048579 0.95 CHKA (0.36) CHKAGPR84KDM4EL3MBTL1PDE5A
SCHEMBL12048100 0.94 CHKA (0.37) CHKAGPR84KDM4EPDE5ALMNA
SCHEMBL12048273 0.93 CHKA (0.39) CHKAGPR84KDM4EL3MBTL1PDE5A
SCHEMBL12047977 0.93 ALDH1A1 (0.36) KDM4EL3MBTL1LMNAMAPTHPGD
SCHEMBL12048344 0.92 PDE5A (0.39) CHKAGPR84KDM4EL3MBTL1PDE5A
SCHEMBL12047845 0.92 PDE5A (0.39) CHKAGPR84KDM4EL3MBTL1PDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9502662-B2 Compound for an organic optoelectronic device, organic light-emitting element comprising same, and display device comprising the organic light-emitting element CHEIL INDUSTRIES, INC. (KR) 2016-11-22 US disclosed
US-9502662-B2 Compound for an organic optoelectronic device, organic light-emitting element comprising same, and display device comprising the organic light-emitting element CHEIL INDUSTRIES, INC. (KR) 2016-11-22 US disclosed
US-20150263291-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING ELEMENT CHEIL INDUSTRIES, INC. (KR) 2015-09-17 US disclosed
US-20150263291-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING ELEMENT CHEIL INDUSTRIES, INC. (KR) 2015-09-17 US disclosed
US-8968884-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2015-03-03 US disclosed
US-8968884-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2015-03-03 US disclosed
US-8410475-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2013-04-02 US disclosed
US-8410475-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2013-04-02 US disclosed
US-8071227-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2011-12-06 US disclosed
US-8071227-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2011-12-06 US disclosed
US-20090200542-A1 Compounds and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2009-08-13 US disclosed
US-20090200542-A1 Compounds and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2009-08-13 US disclosed
US-20090045721-A1 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2009-02-19 US disclosed
US-20090045721-A1 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2009-02-19 US disclosed
US-20080303434-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2008-12-11 US disclosed
US-20080303434-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2008-12-11 US disclosed
US-20080093983-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM. LTD. (KR) 2008-04-24 US disclosed
US-20080093983-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM. LTD. (KR) 2008-04-24 US disclosed
US-20080093982-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2008-04-24 US disclosed
US-20080093982-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2008-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150263291-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING ELEMENT AOX1, OCIAD1, AOC2 CHKA 3620/4885GPR84 1978/4885KDM4E 3431/4885
US-20090200542-A1 Compounds and Organic Light Emitting Device Using the Same CYBA, LOXL1, OGDH CHKA 4022/4885GPR84 4019/4885KDM4E 1584/4885
US-20080303434-A1 Compound and Organic Light Emitting Device Using the Same PPOX, CRY1, CRY2 CHKA 4507/4885GPR84 3641/4885KDM4E 1863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.