Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.32 |
| ▸ | DRD1 known ✓ | P21728 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2801868 | 1.00 | KIF11 (0.42) | KIF11SMN1; SMN2ALDH1A1ITGB1ITGA4 | |
| Hydrochloric Acid SCHEMBL1565157 | 1.00 | KIF11 (0.42) | KIF11SMN1; SMN2ALDH1A1ITGB1ITGA4 | |
| Hydrochloric Acid SCHEMBL2801874 | 1.00 | KIF11 (0.42) | KIF11SMN1; SMN2ALDH1A1ITGB1ITGA4 | |
| Hydrochloric Acid SCHEMBL29401888 | 1.00 | KIF11 (0.42) | KIF11SMN1; SMN2ALDH1A1ITGB1ITGA4 | |
| Hydrochloric Acid SCHEMBL1819809 | 1.00 | KIF11 (0.42) | KIF11SMN1; SMN2ALDH1A1ITGB1ITGA4 | |
| Hydrochloric Acid SCHEMBL1565156 | 1.00 | KIF11 (0.42) | KIF11SMN1; SMN2ALDH1A1ITGB1ITGA4 | |
| Methyl Alcohol SCHEMBL14775370 | 0.98 | KIF11 (0.41) | KIF11SMN1; SMN2ALDH1A1ITGB1ITGA4 | |
| Hydrochloric Acid SCHEMBL4234392 | 0.98 | KIF11 (0.41) | KIF11SMN1; SMN2ALDH1A1ITGB1ITGA4 | |
| Methyl Alcohol SCHEMBL14775372 | 0.98 | KIF11 (0.41) | KIF11SMN1; SMN2ALDH1A1ITGB1ITGA4 | |
| SCHEMBL111171 | 0.98 | KIF11 (0.43) | KIF11SMN1; SMN2ALDH1A1ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119286378-A | Water-based finish paint for outer surface of motor train unit and preparation method thereof | 中国铁道科学研究院集团有限公司金属及化学研究所 | 2025-01-10 | — | — | CN | claimed |
| CN-113209043-B | Intracellular response nanoparticle loaded with target gene siRNA and preparation method thereof | 中山大学孙逸仙纪念医院 | 2023-12-15 | — | — | CN | claimed |
| CN-115154646-B | Degradable hemostatic microsphere and preparation method and application thereof | 国科温州研究院(温州生物材料与工程研究所) | 2023-12-01 | — | — | CN | claimed |
| CN-115154646-A | Degradable hemostatic microsphere and preparation method and application thereof | 国科温州研究院(温州生物材料与工程研究所) | 2022-10-11 | — | — | CN | claimed |
| CN-113171469-B | Tumor treatment nano-drug targeting tumor cell surface Trop2 protein and preparation method thereof | 中山大学孙逸仙纪念医院 | 2022-06-14 | — | — | CN | claimed |
| CN-113817119-A | Preparation method of self-healing waterborne polyurethane with synergistic effect of disulfide bond and multiple hydrogen bonds | 长春工业大学 | 2021-12-21 | — | — | CN | claimed |
| CN-113209043-A | Novel intracellular response nano particle loaded with target gene siRNA and preparation method thereof | 中山大学孙逸仙纪念医院 | 2021-08-06 | — | — | CN | claimed |
| CN-113171469-A | Tumor treatment nano-drug targeting tumor cell surface Trop2 protein and preparation method thereof | 中山大学孙逸仙纪念医院 | 2021-07-27 | — | — | CN | claimed |
| CN-110386890-B | Drug-loaded nano hydrogel based on cysteamine derivatives and preparation method thereof | 沈阳药科大学 | 2021-06-18 | — | — | CN | claimed |
| CN-121177498-A | GSH responsive nano-drug carrier, GSH responsive nano-drug delivery system, and preparation method and application thereof | 中山大学孙逸仙纪念医院 | 2025-12-23 | — | — | CN | disclosed |
| CN-119286378-A | Water-based finish paint for outer surface of motor train unit and preparation method thereof | 中国铁道科学研究院集团有限公司金属及化学研究所 | 2025-01-10 | — | — | CN | disclosed |
| CN-119286378-A | Water-based finish paint for outer surface of motor train unit and preparation method thereof | 中国铁道科学研究院集团有限公司金属及化学研究所 | 2025-01-10 | — | — | CN | disclosed |
| CN-118121745-A | Degradable self-expanding bioactive bone adhesive and application thereof | 广东粤港澳大湾区黄埔材料研究院 | 2024-06-04 | — | — | CN | disclosed |
| CN-113209043-B | Intracellular response nanoparticle loaded with target gene siRNA and preparation method thereof | 中山大学孙逸仙纪念医院 | 2023-12-15 | — | — | CN | disclosed |
| US-6171232-B1 | A DRUG DELIVERY OF NITROVASODILATORS BY A THIOL GROUP AGENT LOADED ONTO A MEDICAL DEVICE SUCH AS A STENT OR A CATHETER | CORDIS CORPORATION | 2001-01-09 | — | — | US | disclosed |
| EP-1018984-A1 | MEDICAL DEVICE FOR $i(IN VIVO) NITRIC OXIDE RELEASE | Cordis Corporation (US) | 2000-07-19 | — | — | EP | disclosed |
| EP-0968997-A2 | Process for S-aryl-L-cysteine and derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2000-01-05 | — | — | EP | disclosed |
| WO-1999000070-A1 | MEDICAL DEVICE FOR IN VIVO NITRIC OXIDE RELEASE | CORDIS CORPORATION (US) | 1999-01-07 | — | — | WO | disclosed |
| US-5646239-A | Organic products containing reactive thiol functions, one method for preparing same, and biomaterials containing said products | FLAMEL TECHNOLOGIES (FR) | 1997-07-08 | — | — | US | disclosed |
| US-5496872-A | Adhesive compositions for surgical use | IMEDEX (FR) | 1996-03-05 | — | — | US | disclosed |