SCHEMBL12580331

SCHEMBL12580331

c1ccc2cc(-c3nc(-c4ccc(-c5nccc6ccccc56)cc4)nc(-c4ccc5ccccc5c4)n3)ccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 1/20 0.49
HTR5A P47898 1/20 0.49
MAPK9 P45984 2/20 0.45
MAPK10 P53779 2/20 0.45
MAPK8 P45983 1/20 0.45
KDM4E B2RXH2 6/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
GPR55 Q9Y2T6 1/20 0.44
MAPT P10636 4/20 0.44
KMT2A Q03164 4/20 0.44
NPSR1 Q6W5P4 2/20 0.44
F2 P00734 1/20 0.44
GLA P06280 1/20 0.44
ALDH1A1 P00352 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
HSD17B10 Q99714 3/20 0.42
CYP1A2 P05177 2/20 0.42
MAPK1 P28482 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12580390 1.00 HTR2B (0.49) HTR2BHTR5AMAPK9MAPK10MAPK8
SCHEMBL15292300 0.97 HTR2B (0.47) HTR2BHTR5AMAPK9MAPK10MAPK8
SCHEMBL2302152 0.93 HTR2B (0.49) HTR2BHTR5AMAPK9MAPK10MAPK8
SCHEMBL17343231 0.92 HTR2B (0.48) HTR2BHTR5AMAPK9MAPK10MAPK8
SCHEMBL12210870 0.91 CYP1A2 (0.47) HTR2BHTR5AMAPK9MAPK10MAPK8
SCHEMBL17944664 0.91 HTR2B (0.50) HTR2BHTR5AMAPK9MAPK10MAPK8
SCHEMBL24091971 0.91 HTR2B (0.42) HTR2BHTR5AMAPK9MAPK10MAPK8
SCHEMBL12210972 0.90 CYP1A1 (0.48) HTR2BHTR5AMAPK9MAPK10MAPK8
SCHEMBL12579285 0.90 CYP1A1 (0.48) HTR2BHTR5AMAPK9MAPK10MAPK8
SCHEMBL10051360 0.90 HTR2B (0.49) HTR2BHTR5AMAPK9MAPK10MAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220165964-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-05-26 US disclosed
US-11329230-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-10 US disclosed
US-20210296591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2021-09-23 US disclosed
WO-2020209299-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE COMPRISING SAME 出光興産株式会社 2020-10-15 WO disclosed
US-20190280211-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-09-12 US disclosed
US-20170317294-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-02 US disclosed
US-20170317294-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-02 US disclosed
US-20170179402-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179402-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20160218297-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-28 US disclosed
US-20160218297-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-28 US disclosed
EP-3048654-A2 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2016-07-27 EP disclosed
US-20160211454-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-21 US disclosed
US-20160211454-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-21 US disclosed
US-9012039-B2 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2015-04-21 US disclosed
US-9012039-B2 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2015-04-21 US disclosed
US-20110156013-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2011-06-30 US disclosed
US-20110156013-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2011-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11329230-B2 Organic light-emitting device EML4, SUN2, TRPA1 HTR2B 2079/4885HTR5A 3482/4885MAPK9 2283/4885
US-20220165964-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME LEF1, OR10J3, RER1 HTR2B 4574/4885HTR5A 4760/4885MAPK9 1354/4885
US-20110156013-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME PPOX, PIEZO1, FTO HTR2B 4605/4885HTR5A 4839/4885MAPK9 208/4885
US-20190280211-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE ALDH1A2, AOX1, AOC3 HTR2B 2581/4885HTR5A 4475/4885MAPK9 408/4885
US-20210296591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE USING THE SAME OLA1, AOC1, ODC1 HTR2B 3860/4885HTR5A 4755/4885MAPK9 1862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.