SCHEMBL126575

SCHEMBL126575

O=S(=O)([O-])c1ccc(Cl)c(Cl)c1.[Na+]

nearest known ligand 0.61

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 known ✓ O43570 1/20 0.42
CA1 known ✓ P00915 1/20 0.42
CA2 known ✓ P00918 1/20 0.42
CA4 known ✓ P22748 1/20 0.42
PTGS2 known ✓ P35354 2/20 0.40
PTGS1 known ✓ P23219 1/20 0.40
LMNA P02545 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
APEX1 P27695 1/20 0.48
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
NFE2L2 Q16236 1/20 0.41
FLT1 P17948 1/20 0.41
FLT4 P35916 1/20 0.41
KDR P35968 1/20 0.41
PTGES2 Q9H7Z7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27781331 0.80 MAPT (0.50) LMNATDP1CA12CA1CA2
SCHEMBL30600038 0.80 LMNA (0.67) LMNATDP1MAPTALDH1A1TP53
SCHEMBL13278270 0.80 LMNA (0.67) LMNATDP1MAPTALDH1A1TP53
SCHEMBL8887426 0.80 LMNA (0.67) LMNATDP1CA2FLT1FLT4
SCHEMBL306417 0.80 PTGS1 (0.50) LMNATDP1CA12CA1CA2
SCHEMBL30343460 0.80 MAPT (0.54) LMNAAPEX1CA12CA1CA2
SCHEMBL2679084 0.80 MAPT (0.54) LMNAAPEX1CA12CA1CA2
SCHEMBL18316 0.78 APEX1 (0.50) LMNATDP1APEX1CA12CA1
SCHEMBL5913739 0.78 APEX1 (0.50) LMNAAPEX1CA12CA1CA2
SCHEMBL867702 0.77 PLCG1 (0.44) LMNATDP1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113061075-A Process for treating wastewater in sulfonation working section of 1, 4-diamino-2, 3-dicyanoanthraquinone 江苏华尔化工有限公司 2021-07-02 CN claimed
CN-107381912-B Comprehensive treatment method of 1, 4-diamino-2-sulfonic acid wastewater 江苏华尔化工有限公司 2020-06-26 CN claimed
EP-3957683-B1 LUMINOUS POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF MITSUBISHI ENG PLASTICS CORP (JP) 2025-10-08 EP disclosed
US-12304998-B2 Polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-05-20 US disclosed
CN-118007260-B Method for producing composite low-melting-point polyester filaments by using regenerated polyester bottle flakes 安徽保尔盈新材料科技有限公司 2024-07-02 CN disclosed
CN-118007260-A Method for producing composite low-melting-point polyester filaments by using regenerated polyester bottle flakes 安徽保尔盈新材料科技有限公司 2024-05-10 CN disclosed
EP-4130152-A1 GLASS-FIBER-CONTAINING FLAME-RETARDANT POLYCARBONATE RESIN COMPOSITION AND MOLDED OBJECT ADEKA CORPORATION (JP) 2023-02-08 EP disclosed
CN-115362213-A Flame-retardant polycarbonate resin composition containing glass fiber and molded article 株式会社ADEKA 2022-11-18 CN disclosed
US-11446899-B2 Transparent film and transparent electrode MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2022-09-20 US disclosed
EP-3279235-B1 INJECTION-MOLDED BODY FOR VEHICLE, AUTOMOBILE LIGHT GUIDE USING SAME, AUTOMOBILE INTERIOR PANEL, AND AUTOMOBILE LAMP LENS MITSUBISHI GAS CHEMICAL CO (JP) 2022-08-31 EP disclosed
US-20220259373-A1 POLYCARBONATE RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2022-08-18 US disclosed
US-7244778-B2 Filler reinforced polyether imide resin composition and molded article thereof GENERAL ELECTRIC COMPANY (US) 2007-07-17 US disclosed
US-20050182166-A1 Reinforced thermoplastic resin composition and molded products thereof MITSUBISHI CHEMICAL CORPORATION 2005-08-18 US disclosed
US-20050131105-A1 Filler reinforced polyether imide resin composition and molded article thereof SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2005-06-16 US disclosed
EP-1497374-A1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GENERAL ELECTRIC COMPANY (US) 2005-01-19 EP disclosed
WO-2003087226-A1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GENERAL ELECTRIC COMPAMY (US) 2003-10-23 WO disclosed
US-6342550-B1 ORGANIC SULFONIC ACID METAL SALT,FLUORINATED POLYOLEFIN, DIENE MULTI-LAYERED POLYMER, PHOSPHORUS FREE; IMPACT RESISTANCE, HEAT RESISTANCE, MOLDABILITY, CHEMICAL REESISTANCE MITSUBISHI ENGINEERING PLASTICS CORPORATION (JP) 2002-01-29 US disclosed
EP-0390064-B1 Fire-retardant polycarbonate resin composition TEIJIN CHEMICALS LTD (JP) 1995-10-11 EP disclosed
US-5045582-A Blend of polycarbonates, high molecular weight, halogen-free TEIJIN CHEMICALS, LTD. (JP) 1991-09-03 US disclosed
EP-0390064-A2 Fire-retardant polycarbonate resin composition Teijin Chemicals, Ltd. (JP) 1990-10-03 EP disclosed