Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342445 | 0.97 | EPHX2 (0.54) | TSHRMAPK1GMNNALDH1A1LMNA | |
| SCHEMBL9416915 | 0.97 | EPHX2 (0.54) | TSHRMAPK1GMNNALDH1A1LMNA | |
| SCHEMBL22390625 | 0.97 | EPHX2 (0.54) | TSHRMAPK1GMNNALDH1A1LMNA | |
| SCHEMBL22390657 | 0.97 | EPHX2 (0.54) | TSHRMAPK1GMNNALDH1A1LMNA | |
| SCHEMBL22390672 | 0.97 | EPHX2 (0.54) | TSHRMAPK1GMNNALDH1A1LMNA | |
| SCHEMBL22390665 | 0.97 | EPHX2 (0.54) | TSHRMAPK1GMNNALDH1A1LMNA | |
| SCHEMBL22390671 | 0.97 | EPHX2 (0.54) | TSHRMAPK1GMNNALDH1A1LMNA | |
| SCHEMBL22390628 | 0.97 | EPHX2 (0.54) | TSHRMAPK1GMNNALDH1A1LMNA | |
| SCHEMBL22390768 | 0.97 | EPHX2 (0.54) | TSHRMAPK1GMNNALDH1A1LMNA | |
| SCHEMBL124865 | 0.97 | EPHX2 (0.54) | TSHRMAPK1GMNNALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026106948-A1 | FIRE RETARDANT COMPOSITIONS CONTAINING ONE OR MORE SURFACTANTS | PERIMETER SOLUTIONS LP (US) | 2026-05-21 | — | — | WO | claimed |
| US-12605321-B2 | Personal care compositions | COLGATE-PALMOLIVE COMPANY (US) | 2026-04-21 | — | — | US | claimed |
| US-20250388596-A1 | PROCESS FOR THE EXTRACTION AND PURIFICATION OF TETRODOTOXIN | WEX PHARMACEUTICALS INC (CA) | 2025-12-25 | — | — | US | claimed |
| CN-120009451-A | Impurity detection method for neostigmine methosulfate injection | 成都苑东生物制药股份有限公司 | 2025-05-16 | — | — | CN | claimed |
| EP-4551585-A1 | PROCESS FOR THE EXTRACTION AND PURIFICATION OF TETRODOTOXIN | Wex Pharmaceuticals Inc. (CA) | 2025-05-14 | — | — | EP | claimed |
| CN-119881130-A | Method for measuring atropine sulfate content in compound aluminum hydroxide tablet | 上海青平药业有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119804678-A | Method for simultaneously detecting contents of two medicinal components in sample | 润尔眼科药物（广州）有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-119780255-A | Method for determining degradation impurities in related substances of vitamin B6 injection | 南京泽恒医药技术开发有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-119757583-A | Method for measuring content of isopalmitin sulfate | 北京吉洛华制药有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119738488-A | Method for measuring optical isomer of eplerenone by high performance liquid chromatography | 江苏嘉逸医药有限公司 | 2025-04-01 | — | — | CN | claimed |
| US-6855852-B1 | Natural gas hydrate and method for producing same | METASOURCE PTY LTD (AU) | 2005-02-15 | — | — | US | claimed |
| EP-1203063-A1 | NATURAL GAS HYDRATE AND METHOD FOR PRODUCING SAME | Metasource Pty Ltd (AU) | 2002-05-08 | — | — | EP | claimed |
| US-6232381-B1 | MIXING WITH SODIUM ALKOXIDE | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-05-15 | — | — | US | claimed |
| CN-1281643-A | Monosultap and abamectin compounded composite and its preparation method | LIYANG CITY CHEMICAL PLANT (CN) | 2001-01-31 | — | — | CN | claimed |
| WO-2001000755-A1 | NATURAL GAS HYDRATE AND METHOD FOR PRODUCING SAME | METASOURCE PTY LTD (AU) | 2001-01-04 | — | — | WO | claimed |
| US-5981639-A | ADDING A SODIUM ALKOXIDE TO THE TIN-COUPLED RUBBERY POLYMER SUBSEQUENT TO THE TIME AT WHICH THE TIN-COUPLED RUBBERY POLYMER IS COUPLED | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-11-09 | — | — | US | claimed |
| CN-1123739-A | Step-curing production method of phenolic glass fiber reinforced plastics | ZHU BAOWEI (CN) | 1996-06-05 | — | — | CN | claimed |
| US-5500668-A | INK JET PRINTING | XEROX CORPORATION (US) | 1996-03-19 | — | — | US | claimed |
| US-5422047-A | Carbonaceous fuel particles | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1995-06-06 | — | — | US | claimed |
| US-4717495-A | BUFFER, CAVITATION LINER PITTING INHIBITOR, CORROSION INHIBITOR, DEFOAMER, SCALE INHIBITOR, DETERGENT | FLEETGUARD, INC. (US) | 1988-01-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12605321-B2 | Personal care compositions | SMURF1, S100A10, SMURF2 | CA2 1029/4885TSHR 3822/4885MAPK1 3869/4885 |
| US-20250388596-A1 | PROCESS FOR THE EXTRACTION AND PURIFICATION OF TETRODOTOXIN | TRPA1, CACNA1D, SCN2A | CA2 260/4885TSHR 119/4885MAPK1 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.