SCHEMBL126874

SCHEMBL126874

c1ccc(-n2c3ccc(-c4cccc(-c5ccc6c(c5)c5cc(-c7ccc8c(c7)oc7ccncc78)ccc5n6-c5ccccc5)c4)cc3c3cc(-c4ccc5c(c4)oc4ccncc45)ccc32)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BTK Q06187 3/20 0.35
PIK3CD O00329 2/20 0.35
PIK3CA P42336 2/20 0.35
PIK3CB P42338 2/20 0.35
PIK3CG P48736 2/20 0.35
PGR P06401 1/20 0.34
CYP19A1 P11511 1/20 0.34
PIK3R1 P27986 1/20 0.34
MTOR P42345 1/20 0.34
PLA2G2A P14555 2/20 0.33
PLA2G4A P47712 2/20 0.33
PLA2G10 O15496 1/20 0.33
TNF P01375 1/20 0.33
KDM4E B2RXH2 3/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ROCK2 O75116 1/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15855292 0.93 PGR (0.38) BTKPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL15855266 0.93 PGR (0.38) BTKPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL15855280 0.92 PLA2G2A (0.39) BTKPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL16887315 0.92 PIK3CD (0.31) BTKPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL15855263 0.90 KDM4E (0.41) BTKPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL15855262 0.90 KDM4E (0.41) BTKPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL15855261 0.90 KDM4E (0.41) BTKPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL10001036 0.89 PIK3CD (0.30) BTKPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL21238864 0.88 HDAC6 (0.34) KDM4EALDH1A1HPGDHSD17B10NPC1
SCHEMBL15855317 0.87 PGR (0.38) BTKPIK3CDPIK3CAPIK3CBPIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 978 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029108-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-02 US disclosed
EP-4329431-A2 NOVEL HETEROLEPTIC IRIDIUM COMPLEXES Universal Display Corporation (US) 2024-02-28 EP disclosed
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
EP-3981776-B1 USE OF AN ANCILLARY LIGAND IN A PHOSPHORESCENT METAL COMPLEX COMPOUND UNIVERSAL DISPLAY CORP (US) 2023-11-15 EP disclosed
US-20230337452-A1 PHOSPHORESCENCE-SENSITIZED DELAYED FLUORESCENCE LIGHT EMITTING SYSTEM UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20110101856-A1 Ion-Pairing Soft Salts Based On Organometallic Complexes And Their Applications In Organic Light Emitting Diodes THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2011-05-05 US disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 US disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 US disclosed
WO-2010111175-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 WO disclosed
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-29 US disclosed
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-29 US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
US-20100072887-A1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORPORATION 2010-03-25 US disclosed
US-20100072887-A1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORPORATION 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12029108-B2 Organic electroluminescent materials and devices LBR, DBF4, DNMT3A BTK 1645/4885PIK3CD 3984/4885PIK3CA 4207/4885
US-20100141127-A1 PHOSPHORESCENT EMITTERS PAICS, TYMP, NUDT1 BTK 2978/4885PIK3CD 835/4885PIK3CA 1415/4885
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LBR, LDLR BTK 1746/4885PIK3CD 4844/4885PIK3CA 4728/4885
US-11917902-B2 Organic electroluminescent materials and devices SOD1, NDUFV1, L1CAM BTK 2767/4885PIK3CD 4416/4885PIK3CA 4444/4885
US-20110101856-A1 Ion-Pairing Soft Salts Based On Organometallic Complexes And Their Applications In Organic Light Emitting Diodes OCIAD2, ICOSLG, OCIAD1 BTK 505/4885PIK3CD 3249/4885PIK3CA 4169/4885
US-20100072887-A1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES SCLY, BZW2, GPX4 BTK 578/4885PIK3CD 4731/4885PIK3CA 4766/4885
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED DDT, FZD7, BRD7 BTK 1060/4885PIK3CD 852/4885PIK3CA 2158/4885
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX DDT, ICOSLG, PDCD1LG2 BTK 1974/4885PIK3CD 1743/4885PIK3CA 3843/4885
US-11832507-B2 Organic electroluminescent materials and devices MLX, LBR, LDLR BTK 1746/4885PIK3CD 4844/4885PIK3CA 4728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.