Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745549 | 0.87 | ALDH1A1 (0.50) | KMT2ALMNARIPK1RIPK3MTNR1A | |
| SCHEMBL4961300 | 0.86 | MTNR1A (0.47) | KMT2ALMNARIPK1RIPK3MTNR1A | |
| SCHEMBL27700413 | 0.84 | KMT2A (0.57) | KMT2ALMNARIPK1RIPK3MTNR1A | |
| SCHEMBL2650122 | 0.84 | LOXL2 (0.54) | KMT2ALMNARIPK1RIPK3MTNR1A | |
| SCHEMBL31074037 | 0.84 | KMT2A (0.55) | KMT2ALMNAMTNR1AMTNR1BMAPT | |
| SCHEMBL19085086 | 0.83 | MTNR1A (0.47) | LMNARIPK1RIPK3MTNR1AMTNR1B | |
| SCHEMBL21554546 | 0.83 | CA2 (0.50) | LMNAMTNR1AMTNR1BALDH1A1EPHX2 | |
| SCHEMBL1283948 | 0.83 | CA2 (0.50) | LMNARIPK1RIPK3MTNR1AMTNR1B | |
| SCHEMBL7517689 | 0.83 | HPGD (0.50) | KMT2ARIPK1RIPK3MTNR1AMTNR1B | |
| SCHEMBL13141325 | 0.83 | RIPK1 (0.43) | KMT2ALMNARIPK1RIPK3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348386-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. | 2023-11-02 | — | — | US | disclosed |
| EP-4234552-A2 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | Raze Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-3426244-B1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-11535593-B2 | 3-phosphoglycerate dehydrogenase inhibitors and uses thereof | RAZE THERAPEUTICS, INC. (US) | 2022-12-27 | — | — | US | disclosed |
| US-20220017464-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. | 2022-01-20 | — | — | US | disclosed |
| US-11014882-B2 | 3-phosphoglycerate dehydrogenase inhibitors and uses thereof | RAZE THERAPEUTICS, INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20190071400-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. | 2019-03-07 | — | — | US | disclosed |
| EP-3426244-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | Raze Therapeutics Inc. (US) | 2019-01-16 | — | — | EP | disclosed |
| WO-2017156179-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| EP-2099776-B1 | CHELATING AGENT | UNIV MUENCHEN TECH (DE) | 2015-10-07 | — | — | EP | disclosed |
| EP-2099776-B1 | CHELATING AGENT | UNIV MUENCHEN TECH (DE) | 2015-10-07 | — | — | EP | disclosed |
| US-20100081799-A1 | Chelating Agent | TECHNISCHE UNIVERSITAT MUNCHEN (DE) | 2010-04-01 | — | — | US | disclosed |
| US-20100081799-A1 | Chelating Agent | TECHNISCHE UNIVERSITAT MUNCHEN (DE) | 2010-04-01 | — | — | US | disclosed |
| CN-101605768-A | Sequestrant | UNIV MUENCHEN TECH (DE) | 2009-12-16 | — | — | CN | disclosed |
| EP-2099776-A1 | CHELATING AGENT | Technische Universität München (DE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008068516-A1 | CHELATING AGENT | Technische Universität München (DE) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348386-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | PHGDH, G6PD, PGD | KMT2A 2306/4885LMNA 3385/4885RIPK1 3600/4885 |
| US-11535593-B2 | 3-phosphoglycerate dehydrogenase inhibitors and uses thereof | PHGDH, G6PD, PGD | KMT2A 2306/4885LMNA 3385/4885RIPK1 3600/4885 |
| US-20100081799-A1 | Chelating Agent | HRH3, C3AR1, H1-3 | KMT2A 365/4885LMNA 4046/4885RIPK1 2876/4885 |
| US-11014882-B2 | 3-phosphoglycerate dehydrogenase inhibitors and uses thereof | PHGDH, G6PD, PGD | KMT2A 2306/4885LMNA 3385/4885RIPK1 3600/4885 |
| US-20190071400-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | PHGDH, G6PD, PGD | KMT2A 2306/4885LMNA 3385/4885RIPK1 3600/4885 |
| US-20220017464-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | PHGDH, G6PD, PGD | KMT2A 2306/4885LMNA 3385/4885RIPK1 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.