Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30444159 | 0.84 | TSHR (0.36) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL490885 | 0.84 | TP53 (0.42) | TSHRMEN1ALDH1A1KMT2ATP53 | |
| SCHEMBL29993141 | 0.82 | — | — | |
| SCHEMBL28520909 | 0.80 | MMP1 (0.46) | — | |
| SCHEMBL30444895 | 0.80 | CA2 (0.42) | TSHRALDH1A1RECQLGLAHPGD | |
| SCHEMBL7978048 | 0.80 | — | — | |
| SCHEMBL11698591 | 0.78 | CA12 (0.35) | TSHR | |
| SCHEMBL28880647 | 0.78 | NR1I2 (0.45) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL486471 | 0.77 | — | — | |
| SCHEMBL9661269 | 0.77 | NR1I2 (0.47) | TSHRRECQLGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457911-A | Low inductance electrolytic capacitor | 京瓷AVX元器件公司 | 2023-07-18 | — | — | CN | disclosed |
| EP-3656576-B1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PRODUCING SAME | FUJIFILM CORP (JP) | 2021-07-14 | — | — | EP | disclosed |
| US-10759209-B2 | Lithographic printing plate precursor, method of producing same, and printing method using same | FUJIFILM CORPORATION (JP) | 2020-09-01 | — | — | US | disclosed |
| EP-3656576-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PRODUCING SAME | Fujifilm Corporation (JP) | 2020-05-27 | — | — | EP | disclosed |
| CN-107206827-B | Lithographic printing plate precursor, method for producing same, and printing method using same | 富士胶片株式会社 | 2020-01-21 | — | — | CN | disclosed |
| US-20190255870-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PRODUCING SAME, AND PRINTING METHOD USING SAME | FUJIFILM CORPORATION (JP) | 2019-08-22 | — | — | US | disclosed |
| US-10322597-B2 | Lithographic printing plate precursor, method of producing same, and printing method using same | FUJIFILM CORPORATION (JP) | 2019-06-18 | — | — | US | disclosed |
| US-10166755-B2 | Planographic printing plate precursor, method of producing same, and printing method using same | FUJIFILM CORPORATION (JP) | 2019-01-01 | — | — | US | disclosed |
| CN-106715139-B | Original edition of lithographic printing plate, the manufacturing method of Driginal plate of plate-printing board and the printing process using original edition of lithographic printing plate | 富士胶片株式会社 | 2018-12-11 | — | — | CN | disclosed |
| EP-3202586-B1 | LITHOGRAPHIC PRINTING PLATE MASTER, MANUFACTURING METHOD THEREFOR, AND PRINTING METHOD USING SAME | FUJIFILM CORP (JP) | 2018-11-28 | — | — | EP | disclosed |
| US-20090075208-A1 | PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2009-03-19 | — | — | US | disclosed |
| US-20090047601-A1 | PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-2011643-A2 | Planographic printing plate precursor and printing method using the same | FUJIFILM Corporation (JP) | 2009-01-07 | — | — | EP | disclosed |
| US-20080318155-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD | FUJIFILM CORPORATION (JP) | 2008-12-25 | — | — | US | disclosed |
| EP-2006091-A2 | Lithographic printing plate precursor and plate making method | FUJIFILM Corporation (JP) | 2008-12-24 | — | — | EP | disclosed |
| EP-2006738-A2 | Lithographic printing plate precursor and lithographic printing method | Fujifilm Corporation (JP) | 2008-12-24 | — | — | EP | disclosed |
| US-20080286685-A1 | PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2008-11-20 | — | — | US | disclosed |
| EP-1992482-A2 | Planographic printing plate precursor and printing method using the same | FUJIFILM Corporation (JP) | 2008-11-19 | — | — | EP | disclosed |
| US-20070214987-A1 | Lithographic printing plate precursor | FUJIFILM CORPORATION | 2007-09-20 | — | — | US | disclosed |
| EP-1834766-A2 | Lithographic printing plate precursor | FUJIFILM Corporation (JP) | 2007-09-19 | — | — | EP | disclosed |