Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16146090 | 0.84 | TP53 (0.50) | TP53MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL128774 | 0.84 | TSHR (0.32) | TP53MEN1ALDH1A1TSHRKMT2A | |
| Lithium Ion SCHEMBL16146088 | 0.78 | TP53 (0.50) | TP53MEN1ALDH1A1TSHRKMT2A | |
| Potassium Ion SCHEMBL16146264 | 0.78 | TP53 (0.50) | TP53MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL7978048 | 0.76 | — | — | |
| SCHEMBL3259690 | 0.76 | LMNA (0.43) | TP53TSHR | |
| SCHEMBL11681921 | 0.76 | TP53 (0.35) | TP53TSHR | |
| SCHEMBL29262165 | 0.75 | TP53 (0.42) | TP53MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL30444159 | 0.75 | TSHR (0.36) | TSHR | |
| SCHEMBL214124 | 0.75 | TP53 (0.42) | TP53MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580723-B2 | Process compositions and production of acyl alkylisethionate compositions | HUNTSMAN PETROCHEMICAL LLC (US) | 2013-11-12 | — | — | US | claimed |
| US-20120094890-A1 | Process Compositions and Production of Acyl Alkylisethionate Compositions | HUNTSMAN PETROCHEMICAL LLC (US) | 2012-04-19 | — | — | US | claimed |
| EP-2021445-A2 | PROCESS COMPOSITIONS AND PRODUCTION OF ACYL ALKYLISETHIONATE COMPOSITIONS | Huntsman Petrochemical Corporation (US) | 2009-02-11 | — | — | EP | claimed |
| WO-2007130390-A2 | PROCESS COMPOSITIONS AND PRODUCTION OF ACYL ALKYLISETHIONATE COMPOSITIONS | HUNTSMAN PETROCHEMICAL CORPORATION (US) | 2007-11-15 | — | — | WO | claimed |
| CN-105163809-B | Hair treatment composition | 荷兰联合利华有限公司 | 2020-06-19 | — | — | CN | disclosed |
| EP-2994198-B1 | HAIR TREATMENT COMPOSITION | UNILEVER NV (NL) | 2019-06-05 | — | — | EP | disclosed |
| EP-1706476-B1 | NOVEL ACYLALKYLISETHIONATE ESTERS AND APPLICATIONS IN CONSUMER PRODUCTS | HUNTSMAN PETROCHEMICAL LLC (US) | 2018-01-10 | — | — | EP | disclosed |
| US-9598358-B2 | Acylalkylisethionate esters and applications in consumer products | HUNTSMAN PETROCHEMICAL LLC (US) | 2017-03-21 | — | — | US | disclosed |
| US-20160081900-A1 | HAIR TREATMENT COMPOSITION | CONOPCO, INC., D/B/A UNILEVER | 2016-03-24 | — | — | US | disclosed |
| EP-2994198-A1 | HAIR TREATMENT COMPOSITION | Unilever N.V. (NL) | 2016-03-16 | — | — | EP | disclosed |
| CN-105163809-A | Hair treatment composition | UNILEVER NV | 2015-12-16 | — | — | CN | disclosed |
| WO-2014000982-A1 | ORAL CARE COMPOSITIONS | UNILEVER PLC (GB) | 2014-01-03 | — | — | WO | disclosed |
| EP-1706476-A1 | NOVEL ACYLALKYLISETHIONATE ESTERS AND APPLICATIONS IN CONSUMER PRODUCTS | HUNTSMAN PETROCHEMICAL CORPORATION (US) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005075623-A1 | NOVEL ACYLALKYLISETHIONATE ESTERS AND APPLICATIONS IN CONSUMER PRODUCTS | HUNTSMAN PETROCHEMICAL CORPORATION (US) | 2005-08-18 | — | — | WO | disclosed |
| EP-1425311-A4 | CYCLODEXTRIN SULFONATES, GUEST INCLUSION COMPLEXES, METHODS OF MAKING THE SAME AND RELATED MATERIALS | EASTMAN CHEM CO (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1425311-A2 | CYCLODEXTRIN SULFONATES, GUEST INCLUSION COMPLEXES, METHODS OF MAKING THE SAME AND RELATED MATERIALS | EASTMAN CHEMICAL COMPANY (US) | 2004-06-09 | — | — | EP | disclosed |
| US-20040054164-A1 | Cyclodextrin sulfonates, guest inclusion complexes, methods of making the same and related materials | EASTMAN CHEMICAL COMPANY (US) | 2004-03-18 | — | — | US | disclosed |
| US-6610671-B2 | Cyclodextrin derivatives for use in cosmetics, pharmacolog, cosmetic, or nutrients | EASTMAN CHEMICAL COMPANY | 2003-08-26 | — | — | US | disclosed |
| US-20020128468-A1 | Cyclodextrin sulfonates, guest inclusion complexes methods of making the same and related materials | BUCHANAN CHARLES M (US) | 2002-09-12 | — | — | US | disclosed |
| WO-2002055562-A2 | CYCLODEXTRIN SULFONATES, GUEST INCLUSION COMPLEXES, METHODS OF MAKING THE SAME AND RELATED MATERIALS | EASTMAN CHEM CO (US) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160081900-A1 | HAIR TREATMENT COMPOSITION | FADS1, AHR, HADH | TP53 3172/4885MEN1 4249/4885ALDH1A1 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.