Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 known ✓ | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B known ✓ | P08514 | 1/20 | 0.52 |
| ▸ | MMP13 known ✓ | P45452 | 2/20 | 0.46 |
| ▸ | MMP8 known ✓ | P22894 | 4/20 | 0.44 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 12/20 | 0.65 |
| ▸ | MMP2 | P08253 | 11/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 3/20 | 0.44 |
| ▸ | MMP14 | P50281 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1499337 | 1.00 | MMP9 (0.65) | MMP9MMP2ITGB3ITGA2BTDP1 | |
| SCHEMBL2038720 | 0.99 | MMP9 (0.67) | MMP9MMP2ITGB3ITGA2BTDP1 | |
| SCHEMBL77677 | 0.99 | MMP9 (0.67) | MMP9MMP2ITGB3ITGA2BTDP1 | |
| Hydrochloric Acid SCHEMBL9087107 | 0.93 | MMP9 (0.74) | MMP9MMP2ITGB3ITGA2BTDP1 | |
| SCHEMBL8001084 | 0.92 | MMP9 (0.76) | MMP9MMP2ITGB3ITGA2BTDP1 | |
| SCHEMBL10585071 | 0.92 | MMP9 (0.76) | MMP9MMP2ITGB3ITGA2BTDP1 | |
| SCHEMBL457772 | 0.92 | MMP9 (0.76) | MMP9MMP2ITGB3ITGA2BTDP1 | |
| Hydrochloric Acid SCHEMBL14059216 | 0.91 | MMP9 (0.68) | MMP9MMP2ITGB3ITGA2BTDP1 | |
| Hydrochloric Acid SCHEMBL28895937 | 0.91 | MMP9 (0.68) | MMP9MMP2ITGB3ITGA2BTDP1 | |
| SCHEMBL8322406 | 0.91 | MMP9 (0.71) | MMP9MMP2ITGB3ITGA2BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260009805-A1 | Platelet Count Assay | INSTR LABORATORY CO (US) | 2026-01-08 | — | — | US | disclosed |
| EP-4675279-A1 | PLATELET COUNT ASSAYS | Instrumentation Laboratory Company (US) | 2026-01-07 | — | — | EP | disclosed |
| US-12060591-B2 | Tau protease compositions and methods of use | OLIGOMERIX, INC. (US) | 2024-08-13 | — | — | US | disclosed |
| US-20200263158-A1 | TAU PROTEASE COMPOSITIONS AND METHODS OF USE | OLIGOMERIX INC (US) | 2020-08-20 | — | — | US | disclosed |
| US-10597649-B2 | Tau protease compositions and methods of use | OLIGOMERIX, INC. (US) | 2020-03-24 | — | — | US | disclosed |
| EP-2709728-B1 | TAU PROTEASE METHODS OF USE | OLIGOMERIX INC (US) | 2019-01-23 | — | — | EP | disclosed |
| US-20170198273-A1 | TAU PROTEASE COMPOSITIONS AND METHODS OF USE | OLIGOMERIX INC (US) | 2017-07-13 | — | — | US | disclosed |
| US-9506051-B2 | Tau protease compositions and methods of use | OLIGOMERIX, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20150297619-A1 | METHODS AND COMPOSITIONS FOR PRESERVING THE MUCOSAL BARRIER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-10-22 | — | — | US | disclosed |
| US-20140286954-A1 | TAU PROTEASE COMPOSITIONS AND METHODS OF USE | Oligomerix, Inc (US) | 2014-09-25 | — | — | US | disclosed |
| EP-2709728-A1 | TAU PROTEASE COMPOSITIONS AND METHODS OF USE | Oligomerix, Inc. (US) | 2014-03-26 | — | — | EP | disclosed |
| WO-2012162179-A1 | TAU PROTEASE COMPOSITIONS AND METHODS OF USE | OLIGOMERIX, INC. (US) | 2012-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260009805-A1 | Platelet Count Assay | PLAT, CTRL, PLG | ITGB3 932/4885ITGA2B 1587/4885MMP13 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.