Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1098660

CCOC(=O)C(N)Cc1ccccc1.Cl

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 known ✓ P23219 1/20 0.59
MMP8 known ✓ P22894 1/20 0.56
HDAC8 known ✓ Q9BY41 2/20 0.49
PPARG known ✓ P37231 1/20 0.47
ALPI P09923 1/20 0.59
PKM P14618 1/20 0.59
XIAP P98170 1/20 0.59
SLC7A5 Q01650 1/20 0.59
SLC15A1 P46059 2/20 0.51
PIN1 Q13526 1/20 0.51
LTA4H P09960 1/20 0.49
SRR Q9GZT4 1/20 0.49
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47
EPHX2 P34913 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TP53 P04637 1/20 0.47
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27531497 1.00 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL216055 1.00 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL27531496 1.00 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL839857 1.00 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
Acetic Acid SCHEMBL28580203 0.98 ALPI (0.58) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL616963 0.98 ALPI (0.61) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL132790 0.98 ALPI (0.61) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL132409 0.98 ALPI (0.61) ALPIPKMPTGS1XIAPSLC7A5
Alcohol SCHEMBL28297579 0.97 ALPI (0.56) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7864444 0.97 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114560811-B 1,3, 5-trisubstituted-pyrazole-4 carboxylic acid derivative, preparation method and application thereof 上海立森印迹医药技术有限公司 2023-09-01 CN claimed
CN-114560811-A 1,3, 5-trisubstituted-pyrazole-4 carboxylic acid derivative and preparation method and application thereof 中国药科大学 2022-05-31 CN claimed
CN-110279886-A It is a kind of with it is anti-oxidant and promote osteogenic ability multi-functional poly phosphazene bone renovating material and preparation method thereof 北京化工大学 2019-09-27 CN claimed
CN-109847455-A A kind of composite material, preparation method and application for filtering fine particulates 四川大学 2019-06-07 CN claimed
CN-106631847-B A kind of synthesis technology of preservative intermediate sorbic acid phenylalanine ethyl ester 上海博栋化学科技有限公司 2018-09-28 CN claimed
CN-106631847-A Synthesis process of preservative intermediate compound phenylalanine ethyl ester sorbate 徐州得铸生物科技有限公司 2017-05-10 CN claimed
CN-104151397-A Novel thiabicyclo organic arsenide compound and synthesis method thereof, as well as application in anti-tumor field UNIV BEIJING 2014-11-19 CN claimed
CN-120041156-A Kerosene phase change material with solid-liquid thixotropic reversible conversion performance 中国科学院化学研究所 2025-05-27 CN disclosed
CN-108348526-B Methods of treating arenaviridae and coronaviridae viral infections 吉利德科学公司 2025-04-25 CN disclosed
CN-119700962-A Preparation method and application of QS-21-polyamino acid nano vaccine 北京化工大学 2025-03-28 CN disclosed
EP-4505875-A1 METHOD FOR CONTROLLING PARASITIC PLANTS AJINOMOTO CO., INC. (JP) 2025-02-12 EP disclosed
US-20250031699-A1 Method for Controlling Parasitic Plants AJINOMOTO CO., INC. (JP) 2025-01-30 US disclosed
CN-119012914-A Method for controlling parasitic plants 味之素株式会社 2024-11-22 CN disclosed
EP-0147211-A2 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation SYNTEX (U.S.A.) INC. (US) 1985-07-03 EP disclosed
US-4325954-A ANTIDEPRESSANTS LABORATOIRES JACQUES LOGEAIS (FR) 1982-04-20 US disclosed
EP-0005248-B1 TETRAPEPTIDEHYDRAZIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION Takeda Chemical Industries, Ltd. (JP) 1982-03-24 EP disclosed
US-4304715-A Enkephalin analogues HUDSON DEREK 1981-12-08 US disclosed
EP-0005248-A2 Tetrapeptidehydrazide derivatives and process for their preparation Takeda Chemical Industries, Ltd. (JP) 1979-11-14 EP disclosed
US-4064236-A Peptide carbazates and pharmaceutical composition MERCK & CO., INC. (US) 1977-12-20 US disclosed
US-3941831-A Resolution of alkyl esters of DL-phenylalanine G. D. SEARLE & CO. (US) 1976-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250031699-A1 Method for Controlling Parasitic Plants PTMS, DAO, GNMT PTGS1 3592/4885MMP8 3923/4885HDAC8 4110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.