Nitrous Acid

Nitrous Acid

SCHEMBL609796

Cl.O=N[O-].[Na+]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Nitrous Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrous Acid SCHEMBL10713889 0.94
Nitrous Acid SCHEMBL6898035 0.94
Nitrous Acid SCHEMBL1331277 0.94
Nitrous Acid SCHEMBL9079679 0.94 ALDH1A1 (1.00)
Nitrous Acid SCHEMBL8933907 0.94
Nitrous Acid SCHEMBL341 0.94
Nitrous Acid SCHEMBL11219505 0.94 ALDH1A1 (1.00)
Nitrous Acid SCHEMBL4730863 0.88
Nitrous Acid SCHEMBL8638727 0.88
Nitrous Acid SCHEMBL10973173 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113149874-B Preparation method of p-methylsulfonyl benzaldehyde 山东国邦药业有限公司 2023-06-06 CN claimed
CN-113149874-A Preparation method of p-methylsulfonyl benzaldehyde 山东国邦药业有限公司 2021-07-23 CN claimed
CN-108459016-A The method of inspection of urea in rubber latex 西双版纳州质量技术监督综合检测中心 2018-08-28 CN claimed
CN-104650618-A Preparation method of dark brown reactive bisazo dye YANG JIQUN 2015-05-27 CN claimed
CN-101230202-A Deep-brown reactive bisazo pigment and preparation method thereof PINGZHONG CHU (CN) 2008-07-30 CN claimed
US-20240208962-A1 MICROBIOCIDAL QUINOLINE/QUINOXALINE BENZOTHIAZINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 US disclosed
CN-115806531-B Preparation method of 4, 5-dihydro-5, 5-diphenyl isoxazole-3-formic acid and derivatives thereof 新发药业有限公司 2024-05-28 CN disclosed
EP-4312556-A1 MICROBIOCIDAL QUINOLINE/QUINOXALINE BENZOTHIAZINE DERIVATIVES Syngenta Crop Protection AG (CH) 2024-02-07 EP disclosed
CN-114790167-B Preparation method of 2, 3-dichloropyridine 北京弗莱明科技有限公司 2024-01-05 CN disclosed
CN-117241668-A Microbiocidal quinoline/quinoxaline benzothiazine derivatives 先正达农作物保护股份公司 2023-12-15 CN disclosed
CN-113149874-B Preparation method of p-methylsulfonyl benzaldehyde 山东国邦药业有限公司 2023-06-06 CN disclosed
CN-115806530-A Preparation method of isoxadifen 新发药业有限公司 2023-03-17 CN disclosed
US-4678499-A PRE- AND POSTEMERGENCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-07-07 US disclosed
US-4670549-A Method for selective methylation of erythromycin a derivatives TAISHO PHARMACEUTICAL CO., LTD. (JP) 1987-06-02 US disclosed
US-4668776-A Protected des-N-methylerythromycin derivative NIPPON ZEON CO. LTD. (JP) 1987-05-26 US disclosed
EP-0203679-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-12-03 EP disclosed
EP-0195960-A1 Method for selective methylation of erythromycin a derivatives TAISHO PHARMACEUTICAL CO. LTD (JP) 1986-10-01 EP disclosed
US-4149872-A N-pyridinyl urea and cyclopropanecarboxamide herbicides SHELL OIL COMPANY (US) 1979-04-17 US disclosed
US-4080329-A DIAZOTIZING 2-AMINO-PYRIDINE-1-OXIDES, TREATING THE DIAZONIUM SALT WITH HYDROCHLORIC OR HYDROBROMIC ACID CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4013763-A MUSCLE RELAXANTS, ANTICONVULSANTS, SEDATIVES, TRANQUILIZERS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-03-22 US disclosed