Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 5/20 | 0.47 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL7532091 | 0.97 | CA2 (0.44) | CA2RECQLCYP3A4TSHRTDP1 | |
| SCHEMBL4961431 | 0.88 | RECQL (0.39) | CA2RECQLCYP3A4TSHRTDP1 | |
| SCHEMBL10420759 | 0.83 | CA2 (0.46) | CA2RECQLCYP3A4TSHRTDP1 | |
| SCHEMBL5254621 | 0.81 | CA2 (0.51) | CA2RECQLCYP3A4TSHRTDP1 | |
| SCHEMBL1423320 | 0.80 | CA2 (0.57) | CA2CYP3A4TSHRTDP1ATM | |
| SCHEMBL1984429 | 0.79 | CES2 (0.37) | RECQLTSHRATMCA1L3MBTL1 | |
| SCHEMBL486057 | 0.79 | CES2 (0.37) | RECQLTSHRATMCA1L3MBTL1 | |
| SCHEMBL10430528 | 0.79 | CES2 (0.37) | RECQLTSHRATMCA1L3MBTL1 | |
| SCHEMBL788087 | 0.79 | CES2 (0.37) | RECQLTSHRATMCA1L3MBTL1 | |
| SCHEMBL6848142 | 0.79 | CES2 (0.37) | RECQLTSHRATMCA1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024038471-A1 | ORAL FORMULATIONS OF EDARAVONE AND IMPROVED METHOD OF MANUFACTURING THEREOF | BDR PHARMACEUTICALS INTERNATIONAL PRIVATE LIMITED (IN) | 2024-02-22 | — | — | WO | claimed |
| US-10414932-B2 | Ink, ink container, and inkjet recording device | RICOH COMPANY, LTD. (JP) | 2019-09-17 | — | — | US | claimed |
| WO-2012125486-A1 | COMBINATION CHEMOTHERAPY FOR TREATING CANCER | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2012-09-20 | — | — | WO | claimed |
| JP-2011530069-A | — | — | 2011-12-15 | — | — | JP | claimed |
| EP-2318815-A1 | FREEZE INDICATORS, COMPONENTS THEREFOR AND PREPARATIVE PROCESSES | Temptime Corporation (US) | 2011-05-11 | — | — | EP | claimed |
| WO-2010014730-A1 | FREEZE INDICATORS, COMPONENTS THEREFOR AND PREPARATIVE PROCESSES | TEMPTIME CORPORATION (US) | 2010-02-04 | — | — | WO | claimed |
| US-20050215700-A1 | Bicomponent adhesive with improved heat resistance and extended pot life | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION | 2005-09-29 | — | — | US | claimed |
| EP-1580244-A2 | Bicomponent adhesive with improved heat resistance and extended pot life | National Starch and Chemical Investment Holding Corporation (US) | 2005-09-28 | — | — | EP | claimed |
| EP-0380154-B1 | Process for the catalytic hydroformylation of olefins | ENIRICERCHE SPA (IT) | 1994-03-09 | — | — | EP | claimed |
| EP-0380154-A2 | Process for the catalytic hydroformylation of olefins | ENIRICERCHE S.p.A. (IT) | 1990-08-01 | — | — | EP | claimed |
| WO-2024038471-A1 | ORAL FORMULATIONS OF EDARAVONE AND IMPROVED METHOD OF MANUFACTURING THEREOF | BDR PHARMACEUTICALS INTERNATIONAL PRIVATE LIMITED (IN) | 2024-02-22 | — | — | WO | disclosed |
| CN-117357410-A | Hair nourishing composition and application thereof | 北京仁生泽发生物技术有限公司 | 2024-01-09 | — | — | CN | disclosed |
| EP-4157953-A1 | WHITE INK, NON-WHITE INK, INK SET, PRINTING SET, PRINTING METHOD, AND PRINTING APPARATUS | Ricoh Company, Ltd. (JP) | 2023-04-05 | — | — | EP | disclosed |
| EP-4110365-A2 | FIDGETIN-LIKE 2 AS A TARGET TO ENHANCE WOUND HEALING | Microcures, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |
| WO-2022246070-A1 | NEEDLE ADAPTOR FOR PLASMA GENERATING HANDPIECE RELATED APPLICATION | Clear Intradermal Technologies, Inc. (US) | 2022-11-24 | — | — | WO | disclosed |
| EP-0558584-A1 | A GEL-FORMING LIQUID DIETARY FIBRE COMPOSITION. | KABI PHARMACIA AB (SE) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992009212-A1 | A GEL-FORMING LIQUID DIETARY FIBRE COMPOSITION | KABI PHARMACIA AB (SE) | 1992-06-11 | — | — | WO | disclosed |
| US-4996366-A | Process for the catalytic hydroformylation of olefins | ENIRICERCHE S.P.A (IT) | 1991-02-26 | — | — | US | disclosed |
| EP-0380154-A2 | Process for the catalytic hydroformylation of olefins | ENIRICERCHE S.p.A. (IT) | 1990-08-01 | — | — | EP | disclosed |
| US-4837136-A | DISPERSIBILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1989-06-06 | — | — | US | disclosed |