Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628847 | 0.83 | CYP11B2 (0.43) | NPSR1PKMCYP11B2GNRHR | |
| SCHEMBL13628854 | 0.80 | MAPT (0.36) | POLBHPGDALDH1A1NPSR1TP53 | |
| SCHEMBL2926951 | 0.78 | PTGS2 (0.48) | POLBHPGDALDH1A1NPSR1PKM | |
| SCHEMBL13628859 | 0.77 | PTGS2 (0.45) | POLBGNRHRTP53 | |
| SCHEMBL13628858 | 0.76 | CCR2 (0.38) | NPSR1PKMTP53LMNA | |
| SCHEMBL13628821 | 0.72 | MAPT (0.37) | HPGDALDH1A1NPSR1TP53RAB9A | |
| SCHEMBL13628860 | 0.71 | PTGS2 (0.46) | GNRHRTP53LMNA | |
| SCHEMBL13628832 | 0.71 | TRPC5 (0.38) | POLBHPGDALDH1A1RAB9A | |
| SCHEMBL13628848 | 0.71 | PTGS2 (0.42) | GNRHRGRIN1GRIN2BLMNA | |
| SCHEMBL13628853 | 0.71 | PTGS2 (0.37) | ALDH1A1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612070-B2 | Heterocyclic compounds as antiinflammatory agents and cyclooxygenase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-11-03 | — | — | US | disclosed |