Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | GNRHR | P30968 | 4/20 | 0.33 |
| ▸ | PARG | Q86W56 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628860 | 0.89 | PTGS2 (0.46) | PTGS2GNRHRLMNAGRIK1GRIK2 | |
| SCHEMBL13628847 | 0.82 | CYP11B2 (0.43) | PTGS2GNRHR | |
| SCHEMBL13628859 | 0.81 | PTGS2 (0.45) | PTGS2GNRHR | |
| SCHEMBL2921335 | 0.80 | PTGS2 (0.60) | PTGS2GNRHRPARG | |
| SCHEMBL13628832 | 0.77 | TRPC5 (0.38) | PTGS2CNR1CNR2 | |
| SCHEMBL13628853 | 0.74 | PTGS2 (0.37) | PTGS2PARGLMNA | |
| SCHEMBL13628850 | 0.74 | PTGS2 (0.36) | PTGS2LMNAGRIN1GRIN2B | |
| SCHEMBL13628824 | 0.74 | RAB9A (0.36) | PTGS2 | |
| SCHEMBL13628821 | 0.74 | MAPT (0.37) | PTGS2PARGLMNA | |
| SCHEMBL13628851 | 0.74 | PTGS2 (0.36) | PTGS2GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612070-B2 | Heterocyclic compounds as antiinflammatory agents and cyclooxygenase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-11-03 | — | — | US | disclosed |