Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680584 | 0.86 | GABRG2 (0.53) | LMNATSHRCCR1CCR8NPC1 | |
| SCHEMBL28928896 | 0.83 | ASIC3 (0.51) | TDP1ALDH1A1ALDH1A3KDM4EMAPT | |
| SCHEMBL4000335 | 0.83 | L3MBTL1 (0.51) | TDP1ALDH1A1ALDH1A3KDM4EMAPT | |
| SCHEMBL2346786 | 0.81 | RARA (0.55) | ALDH1A1KDM4EGAAHPGDCCR1 | |
| SCHEMBL13680472 | 0.81 | CCR1 (0.52) | TGFBR1ALDH1A1MAPTHPGDCCR1 | |
| SCHEMBL13680554 | 0.81 | GRM5 (0.53) | TGFBR1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL13680501 | 0.81 | GRM5 (0.52) | TGFBR1MAPTMEN1KMT2ACCR1 | |
| SCHEMBL302398 | 0.80 | ALDH1A1 (0.50) | TDP1ALDH1A1ALDH1A3KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL3088531 | 0.80 | RARA (0.54) | ALDH1A1KDM4EGAAHPGDCCR1 | |
| SCHEMBL12270020 | 0.80 | TGFBR1 (0.50) | TGFBR1CCR1CCR8CYP2A6GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |