Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CSF1R | P07333 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680497 | 0.83 | KIF11 (0.69) | CSF1RFLT1FLT3MAPTKIF11 | |
| SCHEMBL1886408 | 0.80 | CYP1A2 (1.00) | CYP1A2ALDH1A1MAPTGAATP53 | |
| SCHEMBL3424950 | 0.80 | ALDH1A1 (0.75) | ALDH1A1MAPTKIF11GAATP53 | |
| SCHEMBL8265472 | 0.78 | HSD17B10 (0.66) | CSF1RFLT1FLT3ALDH1A1MAPT | |
| SCHEMBL13680641 | 0.77 | HSD17B1 (0.50) | CYP1A2CSF1RFLT1FLT3ALDH1A1 | |
| SCHEMBL21255476 | 0.77 | FNTA (0.54) | CYP1A2CSF1RFLT1FLT3ALDH1A1 | |
| SCHEMBL19473599 | 0.76 | NPSR1 (0.57) | CYP1A2CSF1RFLT1FLT3MAPT | |
| SCHEMBL1278440 | 0.76 | ALDH1A1 (0.61) | CYP1A2ALDH1A1MAPTKIF11GAA | |
| SCHEMBL13680466 | 0.75 | FAAH (0.56) | CSF1RFLT1FLT3ALDH1A1CNR1 | |
| SCHEMBL13680444 | 0.75 | CNR1 (0.62) | CSF1RFLT1FLT3ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |