SCHEMBL140011

SCHEMBL140011

CC(C)(C)P(c1ccnn1-c1c(-c2ccccc2)nn(-c2ccccc2)c1-c1ccccc1)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
CCNA2 P20248 3/20 0.35
CDK2 P24941 3/20 0.35
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34
PTGS2 P35354 3/20 0.34
PTGS1 P23219 2/20 0.34
POLB P06746 1/20 0.34
MDM2 Q00987 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11998814 0.86 CA1 (0.34) CA1CA2MEN1KMT2ACYP1A2
SCHEMBL1332907 0.83 HTR2A (0.37) CA1CA2MEN1KMT2ACYP1A2
SCHEMBL15200385 0.80 ALDH1A1 (0.37) CA1CA2MEN1KMT2ACYP1A2
SCHEMBL29196807 0.80 CA1 (0.35) CA1CA2MEN1KMT2ACYP1A2
SCHEMBL12930022 0.79 CYP2C9 (0.43) CA1CA2MEN1KMT2ACYP1A2
SCHEMBL28924190 0.79 MEN1 (0.36) CA1CA2MEN1KMT2ACYP1A2
SCHEMBL18806835 0.78 CA1 (0.37) CA1CA2MEN1KMT2ACYP1A2
SCHEMBL18802300 0.78 CA1 (0.37) CA1CA2MEN1KMT2ACYP1A2
SCHEMBL30996356 0.78 CA1 (0.38) CA1CA2MEN1KMT2ACYP1A2
SCHEMBL26684224 0.77 PTGS2 (0.38) CA1CA2MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 620 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062361-A1 PROCESS FOR THE PREPARATION OF BIO-BASED OLEFINS FROM PRIMARY ALCOHOL BASF SE (DE) 2026-03-05 US claimed
EP-4634171-A1 PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE F. Hoffmann-La Roche AG (CH) 2025-10-22 EP claimed
US-20250313551-A1 PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE HOFFMANN-LA ROCHE INC. (US) 2025-10-09 US claimed
US-20250197380-A1 PHARMACEUTICAL INTERMEDIATE AND SYNTHESIS METHOD, AND ISOQUINOLINE DERIVATIVE AND SYNTHESIS METHOD THEREFOR BANGENTAI(SHANDONG) BIOSCIENCES GROUP SHARE CO., LTD. (CN) 2025-06-19 US claimed
WO-2025123046-A1 SYNTHESIS OF LEUCINE-RICH REPEAT KINASE 2 MODULATORS ARVINAS OPERATIONS, INC. (US) 2025-06-12 WO claimed
CN-119930599-A Preparation process of high-purity azilsartan medoxomil 山东鲁宁药业有限公司 2025-05-06 CN claimed
CN-119731143-A Process for the preparation of biobased olefins from primary alcohols 巴斯夫欧洲公司 2025-03-28 CN claimed
CN-119684209-A Preparation method of seven-membered cyclic lysine monomer and copolyamide 中国科学院长春应用化学研究所 2025-03-25 CN claimed
CN-115819412-B Synthesis method and intermediate of N-heterocycle BET bromodomain inhibitor 成都苑东生物制药股份有限公司 2025-03-14 CN claimed
US-12233402-B2 Cross-coupling reaction catalysts, and methods of making and using same YALE UNIVERSITY (US) 2025-02-25 US claimed
US-9045462-B2 Synthesis of an antiviral compound GILEAD SCIENCES, INC. (US) 2015-06-02 US claimed
US-20140275570-A1 SYNTHESIS OF AN ANTIVIRAL COMPOUND GILEAD SCIENCES, INC. (US) 2014-09-18 US claimed
US-8759544-B2 Synthesis of an antiviral compound GILEAD SCIENCES, INC. (US) 2014-06-24 US claimed
US-20140051866-A1 SYNTHESIS OF AN ANTIVIRAL COMPOUND GILEAD SCIENCES, INC. (US) 2014-02-20 US claimed
US-20140051867-A1 SYNTHESIS OF AN ANTIVIRAL COMPOUND GILEAD SCIENCES, INC. (US) 2014-02-20 US claimed
EP-2012779-B1 PROCESS FOR THE PREPARATION OF INDAZOLYL UREAS THAT INHIBIT VANILLOID SUBTYPE 1 (VR1) RECEPTORS ABBOTT LAB (US) 2012-05-16 EP claimed
US-7847104-B2 Process for the preparation of indazolyl ureas that inhibit Vanilloid subtype1 (VR1) receptors ABBOTT LABORATORIES (US) 2010-12-07 US claimed
EP-2012779-A2 PROCESS FOR THE PREPARATION OF INDAZOLYL UREAS THAT INHIBIT VANILLOID SUBTYPE 1 (VR1) RECEPTORS Abbott Laboratories (US) 2009-01-14 EP claimed
WO-2007121339-A2 PROCESS FOR THE PREPARATION OF INDAZOLYL UREAS THAT INHIBIT VANILLOID SUBTYPE 1 (VR1) RECEPTORS ABBOTT LABORATORIES (US) 2007-10-25 WO claimed
US-20070244178-A1 Process for the Preparation of Indazolyl Ureas that Inhibit Vanilloid Subtype1 (VR1) Receptors ABBVIE INC. 2007-10-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070244178-A1 Process for the Preparation of Indazolyl Ureas that Inhibit Vanilloid Subtype1 (VR1) Receptors UTS2R, VIPR1, VRK1 CA1 3426/4885CA2 1596/4885MEN1 2868/4885
US-20140275570-A1 SYNTHESIS OF AN ANTIVIRAL COMPOUND EIF2AK2, SARS1, MAVS CA1 4610/4885CA2 4724/4885MEN1 3345/4885
US-20250197380-A1 PHARMACEUTICAL INTERMEDIATE AND SYNTHESIS METHOD, AND ISOQUINOLINE DERIVATIVE AND SYNTHESIS METHOD THEREFOR PARK7, SQLE, CYP4F11 CA1 3270/4885CA2 4047/4885MEN1 1406/4885
US-20140051867-A1 SYNTHESIS OF AN ANTIVIRAL COMPOUND EIF2AK2, SARS1, MAVS CA1 4610/4885CA2 4724/4885MEN1 3345/4885
US-20140051866-A1 SYNTHESIS OF AN ANTIVIRAL COMPOUND EIF2AK2, SARS1, MAVS CA1 4595/4885CA2 4742/4885MEN1 3111/4885
US-20260062361-A1 PROCESS FOR THE PREPARATION OF BIO-BASED OLEFINS FROM PRIMARY ALCOHOL ADH1C, ADH5, ADH1A CA1 3019/4885CA2 3999/4885MEN1 3331/4885
US-12233402-B2 Cross-coupling reaction catalysts, and methods of making and using same TET2, TIMCC, MDM4 CA1 21/4885CA2 30/4885MEN1 696/4885
US-20250313551-A1 PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE NQO2, SDHA, NDUFS3 CA1 3931/4885CA2 3419/4885MEN1 3994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.