Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340223 | 0.79 | ADRB2 (0.40) | TSHRLMNACYP3A4CYP2C9CASP7 | |
| SCHEMBL20228194 | 0.79 | LMNA (0.39) | TSHRLMNACYP3A4CYP2C9CASP7 | |
| SCHEMBL10245376 | 0.79 | PKM (0.48) | TSHRLMNACYP3A4CYP2C9CASP7 | |
| SCHEMBL20746800 | 0.79 | TSHR (0.42) | TSHR | |
| SCHEMBL22721124 | 0.77 | — | — | |
| SCHEMBL7063746 | 0.77 | CYP2D6 (0.48) | — | |
| SCHEMBL21115026 | 0.76 | LMNA (0.41) | TSHRLMNACYP3A4CYP2C9CASP7 | |
| SCHEMBL756930 | 0.74 | — | — | |
| SCHEMBL437044 | 0.74 | — | — | |
| SCHEMBL12967296 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226225-A1 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | US | disclosed |
| EP-2710018-B1 | MACROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS | FUNDACION CENTRO NAC DE INVESTIGACIONES ONCOLOGICAS CARLOS III (ES) | 2021-12-29 | — | — | EP | disclosed |
| US-20200131285-A1 | NOVEL POLYMERS AND DNA COPOLYMER COATINGS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2020-04-30 | — | — | US | disclosed |
| US-10577439-B2 | Polymers and DNA copolymer coatings | ILLUMINA CAMBRIDGE LIMITED (GB) | 2020-03-03 | — | — | US | disclosed |
| US-20190194363-A1 | NOVEL POLYMERS AND DNA COPOLYMER COATINGS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2019-06-27 | — | — | US | disclosed |
| US-20180155469-A1 | NOVEL POLYMERS AND DNA COPOLYMER COATINGS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2018-06-07 | — | — | US | disclosed |
| US-9815916-B2 | Polymers and DNA copolymer coatings | ILLUMINA CAMBRIDGE LIMITED (GB) | 2017-11-14 | — | — | US | disclosed |
| US-9815916-B2 | Polymers and DNA copolymer coatings | ILLUMINA CAMBRIDGE LIMITED (GB) | 2017-11-14 | — | — | US | disclosed |
| US-9714464-B2 | Precursors for atomic layer deposition | WAYNE STATE UNIVERSITY (US) | 2017-07-25 | — | — | US | disclosed |
| US-20160122816-A1 | NOVEL POLYMERS AND DNA COPOLYMER COATINGS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-05-05 | — | — | US | disclosed |
| US-20150159273-A1 | Precursors for Atomic Layer Deposition | NATIONAL SCIENCE FOUNDATION | 2015-06-11 | — | — | US | disclosed |
| US-20080262226-A1 | METHODS OF MAKING COMPOUNDS HAVING A BETA-ADRENERGIC INHIBITOR AND A LINKER AND METHODS OF MAKING COMPOUNDS HAVING A BETA-ADRENERGIC INHIBITOR, A LINKER AND A PHOSPHODIESTERASE INHIBITOR | ARTESIAN THERAPEUTICS, INC. (CA) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150159273-A1 | Precursors for Atomic Layer Deposition | ADH1A, ADH1C, AKR7A2 | TSHR 4391/4885LMNA 46/4885CYP3A4 321/4885 |
| US-20080262226-A1 | METHODS OF MAKING COMPOUNDS HAVING A BETA-ADRENERGIC INHIBITOR AND A LINKER AND METHODS OF MAKING COMPOUNDS HAVING A BETA-ADRENERGIC INHIBITOR, A LINKER AND A PHOSPHODIESTERASE INHIBITOR | ADRB2, ADRB3, ADRB1 | TSHR 971/4885LMNA 976/4885CYP3A4 686/4885 |
| US-20240226225-A1 | CONJUGATED HEPCIDIN MIMETICS | HAMP, SLC40A1, FTH1 | TSHR 1076/4885LMNA 635/4885CYP3A4 4559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.